There are mainly five causes of renal cysts:
1.Infection factors:Any infection in any part of the body can enter the kidneys through the blood, creating an environment conducive to the change of cyst genes, enhancing the activity of internal factors within the cyst, thereby promoting the formation and growth of the cyst. In addition, infection can also affect the cyst. If the cyst becomes infected, it will not only worsen clinical symptoms but also further accelerate the growth rate of the cyst and exacerbate kidney function damage. Common infection factors include upper respiratory tract infection, urinary tract infection, gastrointestinal tract infection, skin infection, trauma infection, and instrument infection, etc. In other words, whether it is bacterial infection or viral infection, it can have a significant impact on the cyst.
2.Toxins:Toxins acting on the human body can cause damage to various cell tissues and organs, leading to diseases and even life-threatening conditions. They are also one of the main reasons for the occurrence of genetic mutations and congenital developmental abnormalities. Common toxins include pesticides, certain chemical agents, radiation, pollution, and so on. It should be pointed out that some drugs also have nephrotoxicity, and improper use can easily cause kidney damage. These drugs include kanamycin, gentamicin, sulfonamides, rifampicin, indomethacin, and other Western medicine, as well as strychnine and other traditional Chinese medicine.
3.Congenital maldevelopment:Congenital maldevelopment can lead to various diseases. For polycystic kidney disease, it mainly causes medullary sponge kidney, dysplastic polycystic kidney disease, and so on. Genes with congenital developmental abnormalities generally do not have abnormalities, so they are different from genetic inheritance or mutation.
4.mutation of genes:بالنسبة لمرض الكلى المتعددة الكيسات، غالبًا ما ينتقل من الوالدين بطرق الجينات الموروثة، ويتم تقسيمها إلى توريث dominant autosomal و توريث recessive autosomal، ولكن هناك أيضًا بعض مرضى الكلى المتعددة الكيسات الذين ليسوا موروثين من الوالدين ولا ينتمون إلى مرض الكلى المتعددة الكيسات غير الموروثة، بل هم نتيجة تحول جيني أثناء تكوين الجنين. في عملية تكوين الجنين، بسبب تأثير عدة عوامل، يحدث تحول في الجينات مما يؤدي إلى تكوين مرض الكلى المتعددة الكيسات، وقد يحدث هذا الحالة نادرًا، ولكن يمكن أن يحدث، لذلك يمكن لبعض مرضى الكلى المتعددة الكيسات أن لا يكون لديهم تاريخ وراثي للوالدين.
5. ارتفاع ضغط الدم يمكن أن يؤدي إلى تضخم الكيسة:ارتفاع ضغط الدم يمكن أن يؤدي إلى تضخم الكيسة: