In medicine, newborns with excessive weight are called 'macrosomia' (fetal macrosomia). According to the definition of Chinese obstetrics and gynecology, a newborn's birth weight of 4000g or more can be called macrosomia. In the 1980s, macrosomia accounted for only about 3%, but with the rapid economic development and increasingly high material living standards in recent years, the number of pregnant women with macrosomia due to overnutrition has gradually increased, with an incidence rate of about 7% in China, especially in the eastern coastal areas, which has reached 10%. The incidence rate abroad is 15.1%, with more male fetuses than female fetuses. The rate of cesarean section and mortality in macrosomia are significantly higher than those in normal fetuses. When the strength of labor, the birth canal, and the position of the fetus are all normal, labor difficulties often occur due to the large size of the fetus.
Pregnant women with macrosomia often have symptoms such as a heavy abdomen, abdominal pain, and difficulty breathing, and their weight increases rapidly. In addition, the fetal weight can be calculated according to the fundal height and abdominal circumference and the position of the fetus; when the weight is ≥4000g, it may be macrosomia. It can also be predicted by measuring the fetal biparietal diameter, abdominal circumference, and femur length to predict fetal weight; when the fetal biparietal diameter is >10cm and the abdominal circumference/femur length >1.385, there is an 80% to 85% chance of being macrosomia.
The pathogenesis of macrosomia mainly includes genetic factors, hormones and growth factors, as well as environmental factors. The main cause is overnutrition, gestational diabetes mellitus, and heredity.