The main manifestation is swelling of one limb, starting from the ankle and foot, and later involving the entire lower limb. In the early stage, protein-rich lymph fluid accumulates in the tissue spaces, forming soft indented edema, and the skin is still normal. In the late stage, due to the accumulation of protein in the tissue spaces, inflammation and fibrosis of subcutaneous tissue, and other reasons, the edema becomes non-indented, the skin thickens, dries, becomes rough, hyperpigmentation occurs, and warts or spiny-like objects appear.
The degree of lymphedema is divided into:
1, Mild
Limb edema is indented, after elevating the limbs, the edema can decrease or disappear, and there is no fibrosis-like damage to the skin.
2, Moderate
The edema pressure no longer indents, limb elevation does not show significant edema regression, and the skin has moderate fibrosis.
3. Severe
Skin changes similar to elephantiasis appear.
Secondary lymphedema often has recurrent lymphangitis and gradually worsening lymphedema. When lymphangitis occurs, there are local redness, swelling, pain, lymph node enlargement, tenderness, and often accompanied by sudden chills and high fever.