Complex regional pain syndrome (RSD) refers to sudden swelling and pain in the affected hand and shoulder joint pain, which also limits hand function. Due to severe pain and cramps, it becomes a hindrance to rehabilitation, causing diseases such as stroke, myocardial infarction, cervical spondylosis, upper limb trauma, paraplegia, pulmonary diseases, shoulder joint diseases, and unknown causes.
It can be primary, but can also be triggered by various factors, such as minor peripheral nerve injury and central nervous system disorders, acute stroke and spinal cord injury, endocrine diseases, and myocardial infarction, which can all cause shoulder-hand syndrome.
Complex regional pain syndrome is a major cause of disability. It usually affects one limb, but can also affect multiple limbs or any part of the body, with only 1/5 of patients able to fully recover previous activities.