Gonococcal anorectal enteritis is mainly seen in male homosexuals, accounting for40%. Women are more likely to be infected by vaginal self-infection, accounting for35%~50%. The symptoms of rectal gonococcal infection may only include anal itching, painless mucoid purulent discharge, or slight bleeding, or may also manifest with urgency of defecation, purulent stools, congested anal mucosa, purulent discharge. Gonococcus culture is positive. Most male homosexuals have no clinical symptoms. The isolated gonococci are mostly resistant strains, which may be due to the rapid killing of some highly sensitive strains by bile salts or fatty acids in feces. This type of gonococcus is resistant to bile salts and fatty acids, often carrying drug-resistant genes resistant to multiple drugs in the chromosome, making treatment difficult.