Carpal tunnel syndrome, also known as delayed median nerve palsy, is caused by compression of the median nerve within the carpal tunnel. The carpal tunnel is located at the palm root, with its bottom and sides formed by the carpal bones. The transverse carpal ligament crosses over it, forming a bone-fiber channel.
Long-term excessive use of the hand and wrist can cause chronic injury, leading to chronic inflammatory changes in the transverse carpal ligament and the contained tendons, making the lumen narrow is the most common cause. The next is acute injury of the wrist, radial head fracture, and lunate dislocation can cause acute or secondary compression of the median nerve. Certain systemic diseases can cause spontaneous median nerve damage through the enlargement of the contents of the carpal tunnel.
The common age of onset is 30-60 years, five times more common in women than in men, usually unilateral onset, but can also be bilateral. The onset is gradual, with pain, numbness, and tingling in the median nerve distribution area, often waking up from sleep after several hours due to pain, which can be relieved after activity. The skin sensation in the median nerve distribution area is dull and sensitive. The thenar muscle may atrophy, and the thumb may be clumsy and weak. Tinel sign can appear after tapping the wrist, with increased hand sensation after extreme wrist flexion for 60 seconds (Phalen test). The carpal tunnel pressure increases. Hand pain can be induced by inflating the blood pressure cuff for more than 30-60 seconds above the systolic pressure. Overextension and flexion tests of the wrist also cause increased sensory abnormalities and pain. There is tenderness and radiation pain at the carpal tunnel palmar compression point. The conduction velocity of the median nerve is slowed down.
Non-surgical treatment keeps the wrist in a neutral position, and corticosteroids are injected into the carpal tunnel. For those with recurrent attacks that are difficult to alleviate with non-surgical treatment, surgical decompression is required. There are reports of endoscopic surgery.