With the widespread development of spinal surgery, a large number of clinical cases have been observed to find that ossification of the ligamentum flavum in the cervical, thoracic, and lumbar spine is not uncommon in clinical practice, especially after the introduction of advanced technologies such as CT and MRI, the diagnosis rate and detection rate have increased significantly. Among them, there are not a few cases that compress or stimulate the spinal cord, and severe cases may require surgical resection for treatment. The ossification of the ligamentum flavum in the cervical spine has been discussed in a special section.