Hyperbilirubinemia liver pigment deposition syndrome in children

　　Hyperbilirubinemia liver pigment deposition syndrome in children is an autosomal dominant genetic disease caused by a congenital defect in the transport of bilirubin in liver cells. The main clinical manifestation of patients is chronic intermittent jaundice.

　　In addition to its clinical manifestations, hyperbilirubinemia liver pigment deposition syndrome in children can also cause other diseases. This disease can cause liver enlargement and liver function damage. Liver enlargement can be caused by many diseases and is an important clinical sign.

　　The clinical manifestations of hyperbilirubinemia liver pigment deposition syndrome in children are mainly chronic intermittent jaundice. The liver has tenderness or palpable pain, with mild liver enlargement. Jaundice deepens after intense activity or infection.

　　Hyperbilirubinemia liver pigment deposition syndrome in children is a genetic disease with a family history, so it is necessary to focus on genetic counseling work, and carry out premarital health checks and pre-pregnancy genetic counseling in a timely manner. In addition, it is necessary to actively carry out prenatal screening to avoid the birth of affected children.

　　In diagnosing childhood jaundice and liver pigmentation syndrome, in addition to relying on its clinical manifestations, chemical tests are also needed. The main methods of examination are as follows:

　　1. Serum Bilirubin Test

　　The total serum bilirubin level in the laboratory examination was 68.4～153.9μmol/L.

　　2. Liver Function Tests

　　Half of the patients with brain flocculation and musk turbidity are positive.

　　3. Bromosulfophthalein Excretion Test

　　45 minutes after injection, the retention rate is usually 10% to 20%, and the retention rate at 60 minutes and 120 minutes is usually larger than that at 45 minutes, which is a characteristic of the disease.

　　4. Urine Test

　　The examination showed that the level of bilirubin in the urine was increased.

　　Childhood jaundice and liver pigmentation syndrome is a genetic disease, so dietary health care during pregnancy is particularly important. During pregnancy, the diet should be light and nutritious, and attention should be paid to dietary balance. Spicy and stimulating foods should be avoided to prevent recurrence of the disease. Eat more fresh vegetables and fruits and eat more immune-boosting foods to enhance the body's immunity.

　　There is no special treatment for childhood jaundice and liver pigmentation syndrome, and appropriate liver-protective measures can be taken.

　　1. Drinking more water is necessary to take care of the liver

　　Drinking more water can replenish body fluids, enhance blood circulation, and promote metabolism. Drinking more water can also promote the secretion of glands, especially digestive glands and pancreatic juice, bile, to facilitate digestion, absorption, and the excretion of waste products, and reduce the damage to the liver from metabolic products and toxins.

　　2. Pay attention to dietary balance to take care of the liver

　　Do not overeat or starve for a long time. This uneven diet and hunger habits can lead to dysfunction of liver function. The protein, carbohydrates, fats, vitamins, minerals, etc., in food should maintain a corresponding proportion. Try to eat less spicy food and more fresh vegetables and fruits.

　　3. Reduce alcohol intake to take care of the liver

　　The energy for alcohol metabolism in the liver is limited, and excessive drinking will harm the liver, so one should drink less alcohol.