Diseasewiki.com

Home - Disease list page 96

English | 中文 | Русский | Français | Deutsch | Español | Português | عربي | 日本語 | 한국어 | Italiano | Ελληνικά | ภาษาไทย | Tiếng Việt |

Search

Azoospermia

  Azoospermia refers to the situation where sperm is not found in multiple semen examinations (usually more than 3 times). This disease is one of the causes of male infertility. Necessary tests such as testicular biopsy, spermatogenic tract imaging, and endocrine hormone radioimmunoassay can be done to assist in distinguishing between obstructive azoospermia and congenital azoospermia. Azoospermia is often due to congenital deficiency, weak endowment, kidney essence deficiency, and weakened vital fire; or due to postnatal disharmony, excessive depletion, spleen failure in transportation, and lack of source of essence and blood; excessive damp-heat, stasis, and obstruction of the spermatogenic channels; or due to a previous mumps, the epidemic toxin of Shaoyang flowing to Jueyin, and the residual toxin lingering, making it difficult for sperms to be produced and leading to azoospermia. The first step in differentiation is to differentiate between deficiency and excess. Deficiency syndrome is often due to kidney deficiency, often accompanied by decreased libido, impotence, premature ejaculation, lumbar and knee weakness, etc. Excess syndrome is often due to stasis and heat, often accompanied by normal or increased libido, testicular swelling and pain, and hematospermia. The general treatment method is to invigorate the kidney and add essence, and clear heat and remove blood stasis.

  Common causes of testicular spermatogenic dysfunction include: anorchia. The testicles are the only place to produce sperm. Without testicles, the production of sperm is unimaginable. Since there are no testicles, there is no treatment value, and there is no need to take any medicine; bilateral cryptorchidism. This condition is that the testicles have not reached the scrotum where they should be, but stay in the abdominal cavity due to the higher temperature than the scrotum, sperm cannot be produced, and azoospermia can also occur. This condition can be treated by surgery, and it should be noted that the earlier the treatment, the better the effect; congenital incomplete development of the seminiferous tubules (also known as Kline-Felter syndrome), which is also a developmental cause. Although there is no problem with the position of the testicles, there is still a problem with sperm production.

  In real life, it should be avoided to increase the testicular temperature through all factors; consuming cottonseed oil. This oil contains a component called gossypol, which can inhibit sperm production. Therefore, it is used for male contraception. However, if a man who plans to have children eats too much of it, it can lead to a decrease in sperm, even to the point of disappearance. If too much cottonseed oil is consumed, it is difficult to return to normal even after stopping; varicocele. This condition can seriously affect the blood supply to the testicles, thereby affecting the spermatogenic function of the testicles, and can also lead to a significant decrease in sperm or even disappear. Timely surgery or medication (for mild cases) may hope to restore the reproductive function of most patients.

Table of Contents

1. What are the causes of azoospermia
2. What complications can azoospermia easily lead to
3. What are the typical symptoms of azoospermia
4. How to prevent azoospermia
5. What laboratory tests are needed for azoospermia
6. Dietary taboos for patients with azoospermia
7. Conventional Western medical treatment methods for azoospermia

1. What are the causes of azoospermia

  Azoospermia can be divided into two major categories. The first category is testicular spermatogenic dysfunction, where sperm cannot be produced, also known as true azoospermia. The second category is normal spermatogenic function of the testes, but obstructive vas deferens, where sperm cannot be expelled from the body, also known as obstructive azoospermia.
  1. Spermatogenic Disorders
  (1) Genetic diseases: chromosomal or sex chromosome abnormalities can affect spermatogenesis in the testes, such as Klinefelter syndrome.
  (2) Congenital testicular abnormalities: abnormal testicular development or abnormal testicular position can all cause spermatogenic disorders.
  (3) Testicular diseases: such as testicular trauma, inflammation, torsion, and testicular vascular diseases.
  (4) Endocrine diseases, hyperfunction or hypofunction of the pituitary gland, pituitary tumors, hyperfunction or hypofunction of the adrenal glands, hyperthyroidism or hypothyroidism can all affect sperm production and cause azoospermia.
  (5) Severe systemic diseases and malnutrition can lead to azoospermia.
  (6) Factors such as radiation injury and drugs, especially cytotoxic drugs, can damage spermatogenic cells in the testes, which can lead to azoospermia in severe cases.
  2. Obstructive Azoospermia
  Patients have normal secondary sexual characteristics, libido, and sexual function, normal testicular development, and sperm production, but sperm cannot be expelled due to obstructive vas deferens. The causes include: ① Congenital malformations, commonly including ectopic epididymis head, atresia of the epididymis duct, absence or underdevelopment of the vas deferens; ② Infections, such as gonococcal infection, tuberculosis, and other bacterial infections that can cause obstruction of the epididymis and vas deferens; ③ Cysts in the epididymis compressing the epididymis duct to cause obstruction; ④ Injury causing obstruction of the vas deferens.

2. What complications can azoospermia easily lead to

  With the improvement of living standards, azoospermia is becoming more common. Azoospermia is a killer of infertility and sterility, and common complications include:

  1. Damage to the Kidneys

  Azoospermia can lead to weakness of the spleen and stomach, as well as deficiencies in seminal essence and blood, causing kidney essence depletion and harming male fertility.

  2. Causes of Obstructive Vas Deferens

  Due to injury or the accumulation of damp-heat, it can lead to the obstruction of the vas deferens in male friends, causing sperm to be unable to be normally expelled from the body, which is prone to lead to wind-toxin invasion into the Yin meridian in male friends, or the inability to transform sperm.

  3. Leads to testicular spermatogenic function failure

  Generally, it is due to congenital maldevelopment of the testicles, testicular trauma, or inflammation, which interferes with the temperature regulation of the scrotum.

  4. Affects normal male sexual life

  Testosterone is a male androgen in the male body, which is secreted by the interstitial cells of the testicles to maintain male spermatogenic function, as well as secondary sexual characteristics, and control physiological functions. If there is an abnormality, it can affect normal male sexual life.

3. What are the typical symptoms of azoospermia

 

  Common symptoms of azoospermia include:

  1. There is no sperm in the seminal fluid for 3 or more times.

  2. Immunological tests can determine whether there is immunological infertility

  3. Sperm duct造影 can clearly determine whether there is an obstruction in the sperm duct and its location.

  4. Testicular ultrasound can detect gross changes in the testicles, and testicular biopsy can provide more accurate diagnostic and treatment evidence.

  5. If no sperm is found in the centrifugal sedimentation test of seminal fluid for 3 times, it can be diagnosed as azoospermia.

  6. During the physical examination, if the testicular volume is less than 10 milliliters and the texture is abnormally soft, it indicates poor testicular function.

  7. Most patients come to the hospital for infertility examination and are found to have azoospermia after many years of marriage without taking contraceptive measures, and are unable to conceive their wife.

4. How to prevent azoospermia

  In infertile patients, the frequency of azoospermia is 5%-20%, and azoospermia can cause male infertility, seriously harming male health. Experts point out that reducing common radiation exposure, avoiding reproductive organ injuries, and throwing away cigarettes can all prevent the occurrence of azoospermia.

  1. Reduce common radiation exposure in life. Sperm is very fragile, and in the face of strong electromagnetic waves and radiation, it will suffer a disaster. This cause can only be prevented by taking precautions.

  2. Pay attention to avoiding reproductive organ injuries in daily life and work. External injuries that cause testicular injury or torsion, spermatic cord torsion, or due to trauma from hernia repair surgery, prostate surgery, etc., can also affect testicular function and lead to spermatogenic disorders. This situation mainly requires prevention and timely effective measures.

  3. Avoid local high temperature of the testicles in daily life and work. Regular and long-term hot water baths, saunas, or other factors that cause the testicle temperature to rise will affect sperm production, although such cases are mostly associated with oligospermia and excessive sperm death. Avoid all factors that increase testicle temperature.

  4. Usually, varicocele occurs. This condition can seriously affect the blood supply to the testicles, thereby affecting the spermatogenic function of the testicles, and can also lead to a significant decrease or even disappearance of sperm.

  5. Try to reduce the consumption of cottonseed oil in daily life. This oil contains a component called gossypol, which can inhibit sperm production.

  6. Immediately abandon cigarettes. Men who smoke more than a pack a day always have weaker sperm vitality than non-smokers. However, after quitting smoking, one should pay special attention not to be anxious, as this can cause a decrease in testosterone, leading to a decrease in sperm count.

  7. Avoid intense running: Intense running can reduce sperm vitality, so running should be moderate and not too intense. The possibility of oligospermia will also decrease.

  8. Do not rest for too long: Find something light or heavy to do. Do not be lazy, but also do not do heavy physical labor. Rest and physical labor should be moderate.

  9. Do not abstain from sex for a long time: If the genitals are often congested, it will cause the scrotum temperature to rise, resulting in a decrease in sperm vitality. Therefore, it is not advisable to abstain from sex for a long time.

5. What kind of laboratory tests need to be done for oligozoospermia

  The examinations that need to be done for oligozoospermia are:

  1. Endocrine examination: Serum FSH (follicle-stimulating hormone), LH (luteinizing hormone), PRL (prolactin), T (testosterone), DHT (dihydrotestosterone) help distinguish between primary testicular failure and secondary testicular failure.

  2. Obstructive detection: It can detect neutral a-glucosidase and fructose in seminal plasma, because the former is produced by the epididymis, and the latter is produced by the seminal vesicle. By detecting the concentration difference of the two, combined with changes in seminal volume and pH value (normal ejaculation volume is 2-8 ml, pH value is 7.2-8.0, among which seminal vesicle fluid accounts for 70%, and seminal vesicle fluid pH value is alkaline), it can be judged whether there is obstruction, and whether it is in the epididymis, vas deferens, or seminal vesicle, and ejaculatory duct.

  3. Testicular biopsy: Testicular biopsy can clearly diagnose the spermatogenic status of the testis. Due to its certain traumatic factors, the World Health Organization holds a cautious attitude towards it. It is recommended to only perform it in infertile patients with normal testicular volume and normal blood FSH.

  Testicular biopsy (abbreviated as testicular biopsy) is a clinical technique with both diagnostic and therapeutic functions. It is a simple surgical method to remove a small piece of living testicular tissue for pathological section and histological observation to understand the spermatogenic status of the testis, used for diagnosing testicular diseases and evaluating prognosis. Currently, there are also hormone examination methods and biochemical examination methods to understand the spermatogenic function of the testis, which cannot accurately reflect the spermatogenic function of the testis compared to testicular biopsy. Because testicular biopsy directly examines the seminiferous tubules of the testis, while endocrine and biochemical examinations are indirect understanding of spermatogenic function. Currently, testicular biopsy is the gold standard for diagnosing spermatogenic function, so all infertile patients should undergo this examination.

6. Dietary taboos for patients with oligozoospermia

  The diet for oligozoospermia has always been a matter of great concern for patients. It is important to understand that there are still many things to pay attention to in the diet for oligozoospermia. Many people may wonder what is the specific clinical knowledge of diet for oligozoospermia. Below, experts will summarize some diet注意事项 for oligozoospermia for us.

  The diet for oligozoospermia needs to be carefully noticed, everyone should pay attention to understand it clearly. The most common diet care method for oligozoospermia is to eat more zinc-containing foods. Trace element zinc is also a main factor for spermatogenesis, and zinc plays a very important role in maintaining male reproductive function. Zinc can enhance the vitality of sperm. Foods rich in zinc include oysters, shrimps, clams, shellfish, animal liver, walnuts, milk, beans, bran, and lotus seeds, which are necessary. It should be noted that the daily intake of zinc should not exceed 15 micrograms, as excessive zinc intake can affect the function of other minerals in the human body.

  To alleviate the condition of azoospermia, patients with azoospermia can learn more about the dietary care methods for azoospermia. Eat more foods rich in calcium. Calcium affects the activity of sperm. Lack of calcium will slow down the movement of sperm and reduce the activity of acrosin. Foods rich in calcium include milk, dairy products, bone soup, seaweed, shrimp shells, kelp, pomfret, wakame, chrysanthemum, mushrooms, rapeseed, coriander, sweet almonds, dried grapes, etc.

  We must do a good job in the dietary care of azoospermia, do a good job in daily prevention and health care, which is very important for preventing recurrence. The above is the introduction to the diet of azoospermia, hoping to help everyone. In life, everyone can do more of these dietary care methods for azoospermia, which is very effective in alleviating the condition of azoospermia.

7. Conventional methods for treating azoospermia in Western medicine

  Common treatments for azoospermia in Western medicine:

  1. Treatment for true azoospermia caused by spermatogenic disorders: The treatment effect of this type of disease is poor, especially for diseases with severe orchidopagus and pathological changes in the testes. Bilateral cryptorchid patients can still preserve fertility if they undergo early surgical treatment, but if they have not been operated on by the age of 5, the prognosis is poor. For those with low spermatogenic function and FSH values within the normal range, 50mg of clomiphene can be taken daily for 3 months, and if effective, continue taking it until the sperm count recovers to 20 to 60 million/ml. Other drugs such as tamoxifen, HCG, and HMG are also effective.

  2. Treatment for obstructive azoospermia: For those who are blocked due to inflammation and edema of the seminal ducts, antibiotics and corticosteroids can be used; for those caused by cyst compression, the cyst can be surgically removed; for those with congenital malformations or severe developmental abnormalities that cannot be resolved, consideration can be given to artificial insemination with donor sperm (AID) to compensate.

Recommend: Vulvar tumors , Fetal spinal bifida , Breech presentation , Vulvar itching syndrome , Blood seminal fluid , Small penis

<<< Prev Next >>>



Copyright © Diseasewiki.com

Powered by Ce4e.com