Vulvar eccrine adenocarcinoma

　　Etiology:Vulvar eccrine adenocarcinoma mostly originates from large eccrine glands, but can also come from small eccrine glands. Its histological morphology is very similar to normal eccrine glands. The cancer lesion invades the epidermis and has a morphological transition with the adjacent large eccrine glands, and can also infiltrate deeply, sometimes侵入the nerve sheath. The cytoplasm of cancer cells is rich and eosinophilic, and can produce mucus. The degree of differentiation of cancer cells93% are grade I.

　　Vulvar eccrine adenocarcinoma mostly originates from large eccrine glands, but can also come from small eccrine glands. Its histological morphology is very similar to normal eccrine glands. The cancer lesion invades the epidermis and has a morphological transition with the adjacent large eccrine glands, and can also infiltrate deeply, sometimes侵入the nerve sheath. The cytoplasm of cancer cells is rich and eosinophilic, and can produce mucus. The degree of differentiation of cancer cells93% are grade I. Due to surface wear, it can lead to ulceration, and combined with the low resistance and immunity of cancer patients, hemorrhage and infection may occur.

　　One, Symptoms

　　1, Course: The development is usually slow, but a small number of patients have an acute onset, and the course of the disease is1In the past30%, and there are also long-term cases with slowly growing subcutaneous nodules, and sometimes trauma can promote the rapid growth of the tumor.

　　2, Local vulvar itching:is a common symptom of vulvar eccrine cancer, but can also be asymptomatic.

　　3, Vulvar mass: The diameter is usually

　　Two, Signs

　　The eccrine cancer is usually a solitary subcutaneous nodule or mass, with firm texture; it often adheres to the skin, and the skin color of the mass is normal or slightly pink, sometimes with dilated capillaries and occasional serous or hemorrhagic effusion; if the cancer mass is large, it often ulcerates and presents as cauliflower-like masses, accompanied by secondary infection. Physical examination often shows that the tumor is located on the labia majora, with intact skin surface, and may also appear superficial ulcers or eczematous changes. The malignancy of eccrine cancer is low, with slow progression, and in the late stage, the lesion may infiltrate the muscle layer, or involve the vagina and result in inguinal lymph node metastasis and lung metastasis.

　　Vulvar sweat gland cancer is very rare, accounting for only 0. of vulvar malignant tumors.5％. Age of onset30～67years, more common in women than in men.

　　I. Prognosis after treatment

　　Early cases of vulvar sweat gland cancer can be cured after surgical resection. In late cases, lymph node metastasis or lung metastasis may occur, with poor prognosis.

　　II. Prevention

　　1, regular physical examination: to achieve early detection, early diagnosis, and early treatment.

　　2, do a good follow-up: prevent the deterioration of the disease.

　　3, pay attention to personal hygiene, especially the hygiene of the genitals during menstruation and puerperium.

　　4, strengthen the body, improve the body's immunity: pay attention to the combination of work and rest, participate in more physical exercise, and eat more fresh fruits and vegetables rich in vitamins.

　　The examination methods for vulvar sweat gland adenocarcinoma are as follows:

     1, blood routine examination, secretion examination, tumor marker examination.

　　2, X-ray film, ultrasound, radionuclide scan or CT and other imaging examinations; histopathological examination.

　　I. Dietetic formula for vulvar sweat gland adenocarcinoma

　　1, Astragalus and Poria cocos porridge

　　Ingredients: raw Astragalus3grams, Poria cocos5grams, glutinous rice200 grams.

　　Preparation: first decoct Astragalus and Poria cocos into juice, add it to the washed glutinous rice and cook into porridge. It has the effects of invigorating the body, benefiting moisture and detoxifying, suitable for patients with external genital malignant tumors that do not heal.

　　2, mung bean and lotus seed porridge(《Dietary Cancer Prevention Manual》)

　　Ingredients: mung bean5grams, lotus seeds2grams, red dates.

　　Preparation: first cook the lotus seeds until soft, add red dates and mung bean powder, stew15minutes. In the morning and evening2times, it has the effects of invigorating the body and nourishing the blood, invigorating the spleen and removing dampness, and strengthening the body against cancer.

　　3, mushroom egg roll

　　Cut the mushrooms into strips, stir-fry with vegetable oil until done, pour out, add a little salt; beat the eggs, fry into a thin crust, put the stir-fried mushrooms into the crust, roll it up, and serve. Suitable for patients with tumors after surgery and poor taste after radiotherapy and chemotherapy.

　　4, other

　　bitter melon1pieces, beef50 grams, garlic5grams, scallion2grams, chili10grams, sugar, soy sauce, vinegar, and starch as needed. Wash the bitter melon, cut it in half, remove the inside, cut into thin slices, heat the pan, add the bitter melon, and stir-fry2minutes, then pour into a plate; wash the garlic, scallion, and chili, chop them, add oil to the pan, heat it, stir-fry until fragrant, then add the stir-fried bitter melon, add a little salt, sugar, soy sauce, and vinegar, stir-fry with high heat1～2minutes, then pour into a plate; wash the beef, cut into strips, soaked in starch and soy sauce5minutes later, after adding oil to the pan and heating it, stir-fry quickly, add bitter melon, stir a few times and it's done. It can invigorate the spleen and stomach, clear heat and detoxify, and reinforce the body against cancer. Suitable for patients with weak spleen and stomach and irritability due to tumors.

　　5, nourishing double ear soup

　　Black fungus and white fungus each200 grams. Black fungus and white fungus are soaked in water, stir-fried, then added fresh soup and seasonings, thickened and seasoned with starch. It can be used as a nutritious delicacy after surgery and radiotherapy.

　　6Job's tears porridge

　　Firstly, wash Job's tears clean, dry in the sun, grind into fine powder, take this product30-60 grams, mixed with glutinous rice100 grams to make porridge, suitable for breakfast and dinner. Scientific experiments have found that coixenol has the effect of preventing the growth and killing of cancer cells.

　　7Dumplings with scallion and meat

　　Scallion contains a trace of selenium, which has the effect of inhibiting carcinogens in the body, can limit the development of tumors and make them shrink or even disappear. Cut scallion and meat in4:1Make dumplings and steam them for eating. Suitable for all malignant tumors and can prevent the recurrence and metastasis of tumors.

　　Secondly, foods to eat for vulvar sweat gland adenocarcinoma that are good for the body:

　　1Eat more foods with anti-vulvar tumor and leukoplakia effects, such as sesame, almond, wheat, barley, loofah, black chicken, cuttlefish, black gorgon, pork pancreas, chrysanthemum, umeboshi, peach, lychee, horse-tail grass, chicken blood, eel, abalone, crab, sea cucumber, sardine, clam, tortoise shell, etc.

　　2For pain, eat sea cucumber, red, lobster, sea asparagus, sea cucumber, tiger fish, beetroot, mung bean, radish, chicken blood, etc.

　　3For itching, eat amaranth, Chinese cabbage, rapeseed, taro, kelp, nori, chicken blood, snake meat, pangolin, etc.

　　4To enhance physical fitness and prevent metastasis, eat silver ear, black fungus, mushrooms, hedgehog mushrooms, chicken gizzards, sea cucumber, Job's tears, walnuts, crabs, lizard, needlefish, etc.

　　5After vulvar sweat gland adenocarcinoma surgery, consumes qi and injures blood, it is advisable to eat more qi-nourishing and blood-nourishing foods, such as jujube, longan, mung bean, glutinous rice, lychee, mushrooms, carrot, quail eggs, lotus root starch, beans, etc.

　　6Radiation therapy after vulvar sweat gland adenocarcinoma surgery: consumes yin and fluid, it is advisable to eat more yin-nourishing and fluid-nourishing foods, such as spinach, Chinese cabbage, lotus root, radish, watermelon, banana, grape, sea cucumber, sugarcane, lily, etc.

　　7Chemotherapy after vulvar sweat gland adenocarcinoma surgery: easy to damage both qi and blood, it is advisable to often eat foods that nourish qi and blood, such as black fungus, mushrooms, walnuts, mulberries, Job's tears porridge, jujube, longan, sea cucumber, etc.

　　Thirdly, foods to avoid for vulvar sweat gland adenocarcinoma:

　　1Avoid stimulating drinks such as coffee.

　　2Avoid spicy and irritating foods such as scallion, garlic, ginger, cassia, etc.

　　3Avoid greasy, fried, moldy, and preserved foods.

　　4Avoid irritants such as rooster, pork head meat, etc.

　　5Avoid seafood.

　　6Avoid warm foods such as lamb, dog meat, chives, pepper, etc.

　　7Avoid smoking and alcohol.

　　Firstly, traditional Chinese medicine treatment for vulvar sweat gland adenocarcinoma: medication treatment:

　　1Main symptoms of blood heat and dampness toxin type:

　　Skin erythema-like skin lesions or erosive erythema, accompanied by exudate and hemorrhage, foul smell, bleeding upon contact, difficult to stop bleeding, bitter mouth and dry throat, irritability, yellow and red urine, constipated stool, red tongue with greasy yellow fur, slippery and rapid pulse.

　　Therapeutic method: Clear heat, cool blood, and eliminate dampness and poison.

　　Prescription: Yin Hua Detoxification Decoction (from 'Gan Yi Xin De Ji') combined with Bai Bai Shen Shi Shi (from 'Yang Ke Xin De Ji') with modifications.

　　2Main symptoms of liver depression and blood dryness type:

　　Skin papules or small nodules, gradually enlarge, hard texture, raised edges, with ulcers in the middle, not healing after ulceration, accompanied by emotional discomfort, irritability, poor sleep, chest and hypochondrium stuffiness, dry and chapped lips, dry and astringent stool, red tongue with thin yellow or thin white fur, wiry and thin pulse.

　　Therapeutic method: Soothe the liver and regulate the qi, nourish the blood and moisten the dryness.

　　3、 σπασμός του πυκνού πυκνού κύριων συμπτωμάτων:

　　Δερματικές κηλίδες ή κόμβοι, το κέντρο είναι λερώδες ή η άκρη είναι υψηλή, η απόχρωση είναι σκοτεινή, η επιφάνεια είναι ανοιχτή, το τοπικό πόνο, συνοδευόμενο από την ακαμψία της επιφάνειας, η επιφάνεια του προσώπου είναι σκοτεινή, τα χείλη είναι σκοτεινά, η γλώσσα είναι σκοτεινή, υπάρχουν κηλίδες, η πυκνότητα είναι λεπτή.

　　Τεχνική θεραπείας: Ανακουφίστε το αίμα, ενισχύστε την ασθένεια, καταπραΰνετε τη φλεγμονή, αποτοξινώστε.

　　4、 κενό αίματος και αίματος κύρια συμπτώματα:

　　Η ασθένεια είναι μακροχρόνια, η φιλοξενία είναι εξαντλημένη, η επιφάνεια του προσώπου είναι κίτρινη, το οστό είναι σαν το ξύλο, η κατανάλωση είναι κακή, η σπονδυλική στήλη είναι πονεμένη, η κεφαλή είναι σκοτεινή, η πνοή είναι λιγότερη, η γλώσσα είναι λεπτή, η γλώσσα έχει οδοντικά μοτίβα, ο ιστός είναι λεπτός, η πυκνότητα είναι αδύναμη.

　　Τεχνική θεραπείας: Βοηθήστε την ενίσχυση του αίματος και του αίματος, ενισχύστε την ασθένεια και την ασθένεια.

　　Δεύτερο, η θεραπεία της εξωγενής αδένωσης του καρκίνου του κόλπου με τη δυτική ιατρική

　　1、 χειρουργική θεραπεία

　　Η χειρουργική θεραπεία είναι η κύρια μέθοδος για τον καρκίνο των ιδρωτοποιών αδένων, οι εναρκτήτικοί όγκοι μπορούν να εκτελέσουν την ευρεία αφαίρεση του τόπου της λοίμωξης, αν αφαιρεθεί ο όγκος πλήρως, μπορεί να θεραπευτεί. Οι όγκοι της μεσαίας και της μεταγενέστερης περιόδου πρέπει να εκτελέσουν την ευρεία αφαίρεση της εξωγενής αδένωσης, οι ασθενείς με διόγκωση των λεμφαδένων του φακέλου του μηρού πρέπει να εκτελέσουν την αφαίρεση των λεμφαδένων του φακέλου του μηρού. Η έκταση της αφαίρεσης εξαρτάται από το μέγεθος του όγκου.3cm είναι αρκετό. Για τους τεράστιους όγκους, ειδικά για αυτούς που δεν είναι σαφείς στα όρια5cm να κόψει το δέρμα και να εξετάσει την απόσπαση της φιλέτας2～3cm μετά την εξαφάνιση της ευρείας αφαίρεσης. Η έκταση της αφαίρεσης της βάσης πρέπει να καθοριστεί ανάλογα με την βαθιά διείσδυση του όγκου, όταν επηρεάζει τις γειτονικές οργάνους, συχνά πρέπει να αφαιρεθούν τα επηρεασμένα όργανα.

　　Γιατί ο καρκίνος των ιδρωτοποιών αδένων είναι κυρίως τοπικά ενεργητικός, μετά την διείσδυση στην βαθιά, την βάση του να είναι σταθερή και δύσκολο να κινήσει, συχνά συγχέεται ότι δεν μπορεί να αφαιρεθεί χειρουργικά, δεν πρέπει να αμελήσουμε τη θεραπευτική ευκαιρία του ασθενούς. Ο καρκίνος των ιδρωτοποιών αδένων στο μηρό, όταν επηρεάζει την αρτηρία και τον νεύρο, η εξαφάνιση της ημι-οσφυοπέτρου μπορεί να έχει την ελπίδα της θεραπείας.

　　2、 χημειοθεραπεία

　　Ο καρκίνος των ιδρωτοποιών αδένων δεν είναι ευαίσθητος στη χημειοθεραπεία, αλλά η χειρουργική αφαίρεση της εξωγενής αδένωσης και η χημειοθεραπεία μπορεί να βελτιώσει την πρόγνωση, η συνδυαστική χημειοθεραπεία μπορεί να ανακουφίσει προσωρινά τα συμπτώματα. Τα συχνά φάρμακα περιλαμβάνουν φαινυλαλανίνη (CTX), φλουοριούρημα (5-Fu)、 αλκαλοειδή (VCR), βλαστός (BLM), μεθαμεθαμινόλη (MTX), ακτινοβόλο (ACTD) κ.λπ.

　　3、 ακτινοθεραπεία

　　Ο καρκίνος των ιδρωτοποιών αδένων δεν είναι ευαίσθητος στη ακτινοθεραπεία, αλλά για τους ασθενείς που είναι πολύ αργά για την χειρουργική αφαίρεση, μπορεί να δοκιμαστεί η ανακουφιστική ακτινοθεραπεία, μερικές φορές μπορεί να λάβει καλή θεραπεία.