Acute dribbling

　　It is mainly due to excessive intake of spicy and hot foods, fatty and sweet foods; or excessive drinking, leading to damp-heat; or not clearing heat in time due to exposure to summer evil, causing damp-heat to accumulate in the lower jiao; or unclean lower body, causing impure evil to invade the lower jiao, leading to damp-heat; or wind-heat and cold-evil attacking the body, causing the Qi of the Taiyang meridian to be first affected, and leading to damp-heat in the bladder; or due to excessive heart fire, the fire moves to the small intestine. All these causes can lead to damp-heat accumulation in the lower jiao, adverse effects on bladder Qi transformation, and the occurrence of heat dribbling. 'The Source of Various Diseases' says: 'Heat dribbling is due to heat in the Sanjiao, Qi colliding with the kidney, flowing into the bladder to form dribbling, with symptoms of red and涩 urine.

　　It is mainly caused by bacterial infection, any bacteria can cause infection, but the most common is Gram-negative bacilli in the intestines, among which Escherichia coli is the most common, accounting for 70% of urinary tract infections, followed by Proteus, Klebsiella, gas-forming bacteria, alkaline-forming bacteria, Streptococcus beta, Pseudomonas aeruginosa, and Staphylococcus. Since prostatitis and urinary system infections are often caused by sensitive bacteria or pathogenic microorganisms, Western medicine mainly uses broad-spectrum antibiotics for antibacterial and anti-inflammatory treatment; while traditional Chinese medicine, according to dialectical medicine, belongs to damp-heat accumulation in the lower jiao, and the adverse effects of bladder Qi transformation, leading to various prostatic diseases and urinary system infections (i.e., heat dribbling), focuses on clearing heat, promoting diuresis, opening the dribbling, and enhancing immunity, which makes up for the shortcomings of Western medicine and Western medicine, which have a great impact on the liver and kidney, and only focus on treatment without attention to repair and immunity.

　　Dribbling urination is characterized by frequent urination, inability to flow smoothly, and pain after urination. Generally, it is caused by damp-heat in the bladder meridian. However, there are six types of dribbling urination: the first is stone dribbling, which is like sand and gravel, resembling the white alkali that accumulates at the bottom of a pot that has been on the fire for a long time; the main treatment is Yiyuan Powder with amber powder. The second is greasy dribbling, which is like greasy fluid, and is treated with Xianyin Drink. The third is Qi dribbling, where Qi stagnation leads to blockage of the waterway, causing discomfort, distension, and pain around the navel; the main treatment is Jia Su Powder. The fourth is blood dribbling, where blood stasis causes severe pain in the penis, and is treated with Shengdi Four Herbs Decoction plus safflower, peach kernel, and flower stone, or with Daidi Dang Wan. The fifth is fatigue dribbling, which occurs due to excessive labor and exhaustion, indicating Qi deficiency, leading to insufficient Qi transformation in the Zoudu, and is treated with Bu Zhong Yi Qi Decoction. The sixth is cold dribbling, where cold Qi is closed, causing the waterway to fail, with symptoms of cold extremities, cold breath from the nose and mouth, and a preference for hot soup; it is treated with Jin Gui Shen Qi Wan. There are also cases where excessive intake of heat drugs and stones leads to败精 flowing and turning into dribbling. In the elderly, when Yin is weak and there is a desire for sexual activity to lower the essence, the essence does not come out and becomes internal败, leading to pain in urination and defecation like dribbling, the more painful, the more frequent the defecation, and the more frequent the defecation, the more painful. It is advisable to use the previous Xianyin Drink, remove Huang Bai, add Tu Si and Yuan Zhi to guide the essence out, and then use the Six Flavor Decoction to supplement it, which is beneficial. Dribbling symptoms are diverse, and it is not advisable to stick to one treatment method.

　　1. Traditionally, high age, high leukocyte count, Pro-B and T cell phenotype, Ph chromosome, and low haploidy are all manifestations of high-risk acute lymphoblastic leukemia. However, with the use of high-dose intensive therapy and scheme optimization, the leukocyte count is no longer a factor affecting prognosis, and acute lymphoblastic leukemia has reached more than 80% long-term survival.

　　2. Common chromosomal abnormalities in T-ALL often involve TCR rearrangement, and they have no significant impact on prognosis in children receiving intensive treatment; however, in adult T-ALL patients receiving adult treatment, the expression of HOX-11L2 and SIL-TAL1 suggests poor prognosis. High expression of ETS transcription factor ERG is also a factor for poor prognosis in adult acute lymphoblastic leukemia.

　　3. CpG island methylation is a common epigenetic abnormality in various hematological tumors, 88% of T-ALL patients have at least one gene methylation. Research has found that T-ALL patients with 0-2 gene methylation have a 100% 12-year disease-free survival rate, while those with more than 2 gene methylation have only 20%.

　　4. Drug resistance is an important prognostic factor. High expression of multi-drug resistance-related protein-3 (MDP3) indicates poor prognosis for ALL (15). The study by Wiliiems et al. also shows that after one course of chemotherapy, ALL minimal residual disease (MRD) with low expression or negative expression has a 100% 5-year relapse-free survival rate, while those with high expression are only 14±8%; up to the third month of chemotherapy, continuous two positive MRD have a 5-year relapse-free survival rate of 0% (16). Patients who do not respond to one course of BFM-90 and 95 chemotherapy are considered high-risk ALL, with only 47% 5-year disease-free survival.

　　5. The choice of treatment plan determines the prognosis, and the pediatric acute lymphoblastic leukemia plan has a high long-term disease-free survival rate. DFCI uses the pediatric acute lymphoblastic leukemia plan for treatment, with nearly 80% of patients having long-term disease-free survival; while the adult plan is less than 40%.

　　1. Modern medical laboratory examination

　　1. Urinary routine examination.

　　2. Urinary bacterial quantitative culture.

　　3. Urine smear microscopic examination of bacteria.

　　4. Urinary chemical examination: This method is simple and easy to perform, but the positive rate is low, and its value is limited; it cannot replace urine bacterial quantitative culture.

　　5. Urinary leukocyte excretion rate: This is a relatively accurate method for determining leukocyteuria. In the past, the Addis counting method was used, which required the collection of 12 hours of urine. In recent years, the 1-hour urine cell counting method has been adopted. Method: Accurately collect the patient's entire urine for 2 or 3 hours, immediately perform leukocyte counting, and calculate the leukocytes according to 1 hour. Normal people have a positive rate of 300,000/h for leukocytes, between 200,000 and 300,000/h is可疑, with a positive rate of 88.1%.

　　6. Blood routine examination: White blood cell count and neutrophils can increase during the acute phase, and red blood cell count and hemoglobin can slightly decrease during the chronic phase.

　　7. Serological examination.

　　8. Renal function examination: Acute lymphangitis occasionally has dysfunction of urine concentration, which can be restored after treatment.

　　Second, Imaging Examination

　　1. X-ray examination: The abdominal flat film may be unclear due to perinephric abscess. Intravenous urography can detect delayed imaging of calyces and reduced imaging of renal pelvis. It can show primary diseases such as urinary tract obstruction, renal or ureteral malformation, stones, foreign bodies, tumors, etc.

　　2. CT examination: The affected side of the kidney is enlarged and there are wedge-shaped areas of decreased enhancement. It radiates from the collecting system to the renal capsule, and the lesions can be single or multiple.

　　3. Ultrasound examination: shows unclear boundaries between renal cortex and medulla, and areas with lower echo than normal, and can also determine the presence of obstruction, stones, etc.

　　1. Foods that are good for the body for acute lymphangitis

　　Increase water intake and keep it light, eat more vegetables and fruits such as bananas, strawberries, apples, etc. Because they are rich in nutrients, eat more foods that enhance immunity such as propolis. This can enhance personal disease resistance. In daily life, it is also necessary to rationally match the diet and pay attention to sufficient nutrition.

　　2. Foods to avoid for acute lymphangitis

　　Avoid smoking and drinking, spicy and hot foods, greasy foods, and smoking and drinking. Avoid eating cold foods to prevent recurrence of diseases.

　　First, Yiyuan San

　　1. Baijie Drink, for treating damp stranguria, and for treating various strangurias.

　　2. Baijie (three qian) Wenhaofen (ground into fine powder) Shiwei Cheqianzi Fuling (each one liang five fen) Dengxin (twenty joints) Lianzixin Shigepi Huangbai each eight fen.

　　Second, Su San (powder)

　　1. Treatment of Qi stranguria. Jingjie Chenpi Xiangfu Maiya (fried) Qumai Mutong Chihuangfu in equal parts ground into powder. Take three qian with boiling water each time.

　　2. Shengdi Siwu Decoction (that is, the Four Substances Decoction with Shengdi instead of Shuadi for deficiency of Qi and labor.).

　　Three Generations Diding Pill

　　Shengdi Danggui Chishao (each one liang) Chuanxiong Wulingzi (each seven liang five fen) Da Huang steamed with wine, one liang and five qian of sugar made into pills. Take three qian with boiling water each time.