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Pseudomegakaryocytic syndrome

  This syndrome refers to a syndrome characterized by ascites and pleural effusion associated with pelvic tumors, and the ascites and pleural effusion may not necessarily disappear after tumor resection as the main manifestation. It is mostly associated with malignant tumors in the ovary, fallopian tube, uterus, and other parts, especially those with peritoneal implantation or metastasis.

 

Table of Contents

1. What are the causes of pseudomegakaryocytic syndrome?
2. What complications can pseudomegakaryocytic syndrome lead to?
3. What are the typical symptoms of pseudomegakaryocytic syndrome?
4. How to prevent pseudomegakaryocytic syndrome?
5. What laboratory tests are needed for pseudomegakaryocytic syndrome?
6. Dietary taboos for patients with pseudomegakaryocytic syndrome
7. Conventional methods of Western medicine for the treatment of pseudomegakaryocytic syndrome

1. What are the causes of pseudomegakaryocytic syndrome?

  1. Etiology

  The main cause of ascites in this syndrome is the malignant tumors associated with the ovary, fallopian tube, uterus, and other parts, especially those with peritoneal implantation or metastasis. Benign papillary cystadenoma and mucinous cystadenoma can implant in the peritoneum due to the penetration of papillae through the cyst wall, and can also produce a large amount of ascites.

  2. Pathogenesis

  Pseudomegakaryocytic syndrome is not ovarian fibroma, but other types of benign and malignant tumors of the ovary, pancreatic diseases, or tumors in other parts. The main cause of ascites in pseudomegakaryocytic syndrome is the malignant tumors associated with the ovary, fallopian tube, uterus, or round ligament, especially those with peritoneal implantation or metastasis. Epithelial papillary carcinoma, due to the penetration of papillae through the cyst wall, can implant in the peritoneum. These implanted or metastatic tumor cells in the peritoneum can secrete and its decomposition products can chemically stimulate the peritoneum, causing ascites; it can also come from the rupture of ovarian tumors, with the tumor contents continuously渗入腹腔 forming ascites; it can also reach the pleural cavity through the diaphragm or lymphatics, causing pleural effusion.

 

2. What complications can pseudomeig syndrome easily lead to

  1, Recurrent ascites:The formation of ascites is the result of the loss of dynamic balance between the production and absorption of fluids in the peritoneal cavity. The formation mechanism of ascites in each disease is caused by the combined or single action of several factors.

  2, Pleural effusion:Especially in patients with peritoneal implantation or metastasis, epithelial papillary carcinoma, due to the papilla piercing the cyst wall and implanting in the peritoneum, these implanted or metastatic tumor cells in the peritoneum can secrete and its decomposition products can chemically stimulate the peritoneum, causing ascites; it can also come from the rupture of ovarian tumors, with the tumor content continuously渗入腹腔 forming ascites; it can also reach the pleural cavity through the diaphragm or lymph, causing pleural effusion.

3. What are the typical symptoms of pseudomeig syndrome

  The clinical manifestations of pseudomeig syndrome are similar to those of true meig syndrome. Most ascites are brown-red, hemorrhagic ascites, sometimes mixed with mucus or tumor content. The ascites is thick and turbid. Through centrifugal precipitation, smears can sometimes be found, and cancer cells can be found, so abdominal puncture, taking ascites samples for examination, is conducive to diagnosis and differentiation.

 

4. How to prevent pseudomeig syndrome

  After Meig and Cass elaborated on 7 cases of meig syndrome in 1937, Meig proposed pseudomeig syndrome in the obstetGynecol journal in 1954. In 1968, Brenner and Scott reported this syndrome with the title 'Meig syndrome secondary to Krukenberg tumor':

  Prognosis: The prognosis of this syndrome depends on the nature of the tumor and whether there is metastasis. Generally poor, the prognosis may be slightly better before surgery.

 

5. What laboratory tests are needed for pseudomeig syndrome

  Hormone determination, if this syndrome is caused by a functional tumor, the corresponding hormones will increase, for example, in patients with ovarian primary choriocarcinoma, chorionic gonadotropin can be detected in blood and urine:

  1, Ultrasound examination:Ultrasound examination can assist in diagnosing the location of the tumor, to distinguish between cystic or solid tumors.

  2, Characteristics of ascites examination:Most ascites in pseudomeig syndrome are hemorrhagic, and cancer cells can be found; while true meig syndrome ascites is clear; in pseudomeig syndrome, some tumor markers can often be found in ascites. Histopathological examination is the golden standard for diagnosing the disease. After surgical resection of the tumor, or laparoscopic biopsy, is the only method to clearly diagnose this syndrome.

6. Dietary taboos for patients with pseudomeig syndrome

  First, food therapy recipe

  1, Corn silk 30 to 60 grams, winter melon seeds 15 grams, red beans 30 grams, decocted in water for oral administration, 1 dose per day, 15 doses as one course.

  Effect: Diuretic and edema-reducing, treating ascites.

  2, Mungo beans 500 grams, pig gallbladders 4. Adjust mungo bean powder with pig gallbladder juice into pills (the size of mungo beans), take 3 times a day, 6 to 9 grams each time, until finished.

  Effects: diuretic and edema-relieving.

  Boil 50 grams of red beans, then add a kilogram of crucian carp (with the internal organs and scales removed), without adding oil, salt, vinegar, and other seasonings.

  Take all at once before or with breakfast, for severe cases, take two doses a day, for mild cases and the stage of consolidating efficacy, only half a dose is needed.

  500 grams of eels, with the gills and internal organs removed, washed clean, add a little salt (do not add for those with obvious ascites), add an appropriate amount of water, simmer until five degrees of maturity, add 250 grams of tofu, and then simmer until the fish is soft and tender. Eat the fish, tofu, and drink the soup, and eat in separate servings.

  Effects: tonify the middle and vital energy, clear and drain damp-heat.

  Second, dietary taboos

  1. Diet should be light and nutritious.

  2. Eat more foods containing anticancer substances: vegetables, radishes, plums, soybeans, beef, mushrooms, asparagus, Job's tears, etc.

  3. Eat more fruits, milk, turtle, etc., which are rich in various amino acids, vitamins, proteins, and easily digestible tonifying foods.

  4. For patients with high fever and injury to the body fluid, pear juice or apple juice, watermelon juice, etc., can be given.

  5. Patients with yellow, abundant, and thick leukorrhea should avoid eating fried and greasy, spicy foods.

  6. For tumor patients with cold pain in the lower abdomen, fear of cold, and back pain, give ginger soup, brown sugar water, and longan meat, etc., which are warm and hot in nature.

  7. People with five heart flurries and back pain should eat more meat and eggs, which are rich in blood and flesh, to nourish and strengthen the body.

  8. Limit salt and sodium in the diet.

  9. The daily water intake should be limited to 1000-1500 milliliters.

  10. Eat less greasy and heavy foods.

  11. Avoid spicy, sour, salty, and stimulating foods such as alcohol and tobacco.

  12. Eat less drinks and snacks containing chemicals, preservatives, and additives.

  13. Eat less of the 'trigger foods' that are easy to cause allergies: shellfish without shells, bamboo shoots, taros, etc.

7. Conventional methods for treating pseudomacroglobulinemia with Western medicine

  1. Regular check-ups to ensure early detection and diagnosis.

  2. Perform surgery as soon as possible and follow up after surgery.

  As an auxiliary treatment method, some traditional Chinese medicine extracts such as Panax ginseng saponins Rh2 (Huoming Su) can be used to tonify vital energy, increase white blood cells, enhance the body's immune and resistance, inhibit the growth and proliferation of cancer cells, induce cancer cells to transform into normal cells, which can improve the quality of life of patients and extend their lifespan.

 

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