Pseudomonas alli pneumonia

　　Pseudomonas alli is one of the non-fluorescent Pseudomonas, widely growing in the external environment, and was first discovered as a plant pathogen that can cause rot in onion bulbs. It can survive in various disinfectants such as benzalkonium chloride (Jiermi), chlorhexidine, and polyene pyrrolidone iodine, thereby causing an outbreak of hospital-acquired infections caused by Pseudomonas alli. It can lead to endocarditis, sepsis, postoperative and burn wound infections, peritonitis, osteomyelitis, arthritis, meningitis, pneumonia, lung abscess, and therefore, this bacterium can be detected in the blood, urine, pus, pleural effusion, and bronchoalveolar lavage fluid of these patients. The strong reproductive growth ability of this bacterium and its resistance to many disinfectants and preservatives currently used make it a difficult-to-treat hospital-acquired infection pathogen. Some strains of Pseudomonas alli are more infectious and pathogenic than others. Some strains are associated with most newly occurring infections, and infections occurring in different regions are also related to individual strains.

　　Pseudomonas aeruginosa is an opportunistic pathogen with low pathogenicity to healthy humans and animals. Some patients may have Pseudomonas aeruginosa growing in their sinuses, leading to aspiration pneumonia. Most strains produce proteases (gelatinases) and lipases. The bacteria may directly destroy lung tissue by releasing toxins and enzymes, causing necrotizing pneumonia or other types of pneumonia, lung abscesses, etc.; some strains can synthesize phthalocyanine pigments, which can block the proliferation of lymphocytes. Some patients may also have immune complex formation involved in tissue destruction, such as in the case of concurrent Pseudomonas aeruginosa infection, which may have a synergistic effect with Pseudomonas aeruginosa.

　　Pseudomonas aeruginosa pneumonia often complicates with other serious diseases, such as malignant tumors and cystic fibrosis, which can cause recurrent high fever, progressive weight loss, sudden and fatal deterioration of the condition, and death within a short period of time. Female patients often have more severe clinical symptoms and poorer prognosis than male patients. Severe bacterial infection, a sharp decline in lung function, often accompanied by other serious diseases, and a few patients may have bacteremia. The decline in lung function in patients with Pseudomonas aeruginosa pneumonia is more severe than that in patients with Pseudomonas aeruginosa pneumonia.

　　Pseudomonas aeruginosa pneumonia has three types of clinical manifestations, as follows:

　　1. Long-term asymptomatic carriage of the bacteria.

　　2. Progressive deterioration over several months, recurrent high fever, progressive weight loss, and repeated hospitalizations.

　　3. Sudden and fatal deterioration of the condition, death within a short period of time.

　　Female patients often have more severe clinical symptoms and poorer prognosis than male patients. The typical clinical course is severe bacterial infection, characterized by recurrent or persistent high fever, progressive weight loss, and a sharp decline in lung function, often accompanied by other serious diseases (such as malignant tumors, cystic fibrosis), and a few patients may have bacteremia. The decline in lung function in patients with Pseudomonas aeruginosa pneumonia is more severe than that in patients with Pseudomonas aeruginosa pneumonia.

　　In view of the spread of the bacterium through direct contact and social contact, patients infected with Pseudomonas aeruginosa should be isolated from those who have not been infected, and their social activities should be restricted, but the latter often face opposition from patients and there is controversy. Medical personnel should wash their hands after contacting patients to reduce the opportunity for cross-infection. Avoid sharing nebulizers to prevent cross-infection, and disassemble the nebulizers daily to soak in sodium hypochlorite solution for disinfection, and sterilize them under high pressure once a week. For patients with sinusitis, sinus puncture should be performed to reduce the source of infection.

　　The main clinical examination methods for Pseudomonas aeruginosa pneumonia are laboratory examination and auxiliary examination. The specific details are as follows:

　　First, laboratory examination

　　1, bacteriological examination: different strains or ribotypes have different pathogenicity, and ribotypes are useful for evaluating the relative risk of infection in patients with cystic fibrosis before lung transplantation. According to the condition, sputum, bronchoalveolar lavage fluid, pleural effusion, blood, ascites, urine, and other specimens can be taken.

　　2, peripheral blood: leukocyte count increased, erythrocyte sedimentation rate accelerated, C-reactive protein increased.

　　Second, auxiliary examination

　　X-ray manifestations: lung substance infiltration is often lobular, occasionally there are extensive changes, and空洞 formation may occur. Pulmonary function FEV1, FEV1/FVC progressively decrease.

　　For patients with Pseudomonas aeruginosa pneumonia, it is advisable to eat foods with therapeutic effects,清热解毒 and rich in trace elements such as calcium and iron, and to avoid eating greasy, thick, high-potassium, spicy, overly sour or cold刺激性 foods. You can also improve symptoms through the following food therapy methods:

　　1, Stir-fried Crucian Carp with Celery

　　Ingredients: 250g crucian carp, 50g fresh celery, starch, ginger strips, garlic strips, soy sauce, sugar, vinegar, monosodium glutamate, cooking wine, pickled hot peppers, and vegetable oil in appropriate amounts. Preparation: Cut the crucian carp into strips, cut the celery into segments, mix soy sauce, sugar, vinegar, monosodium glutamate, cooking wine, salt, and starch with broth to make a sauce. Heat a wok over high heat, add oil, heat to 5 degrees, add fish strips, stir-fry and drain excess oil, add ginger strips and pickled hot peppers. Stir-fry the celery segments until fragrant, then add the sauce, add bright oil, and remove from heat. Benefits: Crucian carp has the effects of clearing heat and detoxifying, promoting diuresis and reducing swelling, stopping cough and relieving asthma; celery has the effects of calming the liver and clearing heat, dispelling wind and removing dampness, and nourishing the spirit and building Qi. Eating crucian carp and celery together is suitable for the adjuvant treatment of acute and chronic pneumonia.

　　2, Rabbit Meat and Mushroom Strips

　　Ingredients: 100g cooked rabbit meat, 50g mushrooms, 25g scallion, chili oil, soy sauce, vinegar, sugar, sesame oil, sesame paste, Sichuan pepper powder, and monosodium glutamate in appropriate amounts. Preparation: Cut the cooked rabbit meat and scallion into strips, and cook the mushrooms. Place the scallion and mushrooms at the bottom, cover with rabbit strips, and serve in a dish. Dilute the sesame paste with soy sauce in several steps, mix with sesame oil to make a sauce, and pour it over the rabbit strips. Benefits: Rabbit meat has the effects of clearing heat and detoxifying, invigorating the spleen and building Qi, removing dampness and cooling the blood, and promoting defecation; mushrooms have the effects of detoxifying and moistening the dryness, invigorating the spleen and building Qi, and stopping diarrhea. Eating rabbit meat and mushrooms together is suitable for treating acute pneumonia.

　　3, Quail Lily Soup

　　Ingredients: Quail 1, Lily 25g, ginger, scallion, monosodium glutamate, and fine salt in appropriate amounts. Preparation: Kill the quail, remove feathers, feet, and internal organs, wash clean, blanch in boiling water, remove and cut into pieces; separate the lily petals, wash, and set aside. Wash the ginger and scallion, crush the ginger, and cut the scallion into segments. Place a pot on a high heat, add some water, add the quail, bring to a boil, add lily petals, ginger pieces, and scallion segments, then simmer on low heat until the quail is cooked. Add salt and monosodium glutamate, cover and simmer for several minutes, then serve in a soup bowl. Benefits: Quail meat has the effects of nourishing the five internal organs, benefiting the liver and clearing the lungs, clearing heat and removing dampness, resolving accumulation and stopping diarrhea; lily has the effects of moistening the lungs and stopping cough, nourishing yin and clearing heat, calming the mind. Eating both together is suitable for acute and chronic pneumonia.

　　4. Lean meat and cabbage soup

　　Ingredients: raw lean meat, 100 grams of cabbage heart, a little ginger, garlic, salt, monosodium glutamate, chicken oil. Preparation: slice the lean meat, wash and slice the cabbage, put it in boiling water, remove it when it is just cooked, rinse it clean in cold water, filter dry the water and set aside; place the pot on a high heat, add chicken oil to 50% maturity, add garlic and stir-fry it to a golden color, then add the lean meat and stir-fry together, add fine salt, cook in the soup, then add the cabbage heart and bring to a boil, add monosodium glutamate and it is ready to eat. Effect: lean meat has the effect of invigorating the middle, nourishing the Qi, moistening the intestines, and promoting bowel movements; cabbage is mild in nature and sweet in taste, with the effects of clearing heat and detoxifying, resolving phlegm and stopping cough, relieving restlessness and promoting bowel movements. Eating lean meat and cabbage together is suitable for acute and chronic pneumonia.

　　Pseudomonas syringae is naturally resistant to most commonly used antibiotics. It is resistant to first and second generation cephalosporins and traditional pseudomonas penicillins such as ticarcillin. Cefotaxime (cefotaxime carboxyhydrate) is effective against 84.7% of the strains, doxycycline is effective against 63.5% of the strains. Early selective intravenous administration of tobramycin, cefotaxime (cefotaxime carboxyhydrate), chloramphenicol, and sulfamethoxazole may be effective, and tobramycin can also be inhaled via nebulization. Some experts also point out that although Pseudomonas syringae is resistant to most antibiotics in vitro, combined chemotherapy (such as the combination of aminoglycoside antibiotics and β-lactam antibiotics) may still be effective. This is because the sensitivity of antibiotics in vitro cannot represent the internal environment conditions during pulmonary inflammation, and the body's response may be a comprehensive effect of antibiotics. The antibiotic sensitivity test currently used for Pseudomonas syringae may be inappropriate, as this bacterium grows slower than Pseudomonas aeruginosa and is easy to grow at 30°C. It is also possible that the large growth of Pseudomonas syringae may affect the identification of other bacteria, such as Staphylococcus aureus and Haemophilus influenzae.