Clinical practice has proven that for patients in the middle and advanced stages, large doses of radiotherapy and chemotherapy, or rechemotherapy for patients with drug resistance, can only lead to the life of weakness becoming more dangerous, accelerating the death of patients. Clinically, it is often seen that the cause of death of patients is not due to cancer itself, but due to unscientific and inappropriate killing treatment. For example, after multiple interventional treatments for liver cancer, ascites and jaundice occur, leading to liver failure and death; after chemotherapy for pleural effusion in lung cancer, respiratory failure occurs and death; after chemotherapy for gastric cancer and colorectal cancer, nausea and vomiting occur, and the patients become more exhausted and die; with decreased leukocytes, the patients die from infection, etc.
Firstly, do a good job in the three-level prevention of tumors.
1, Syndrome of Phlegm-heat Retention:
Swelling nodes in the neck or inguinal region, or with feeling of fullness in the epigastrium and abdomen, severe fever, often with night sweats, dry mouth and thirst, swelling and pain in the throat, irritability and insomnia, or with skin itching, or yellowing of the body and eyes, dry stools or hematochezia, oliguria, red tongue with dry and yellow fur or red and绛 without fur, thin and rapid pulse or thin and slippery.
Treatment method: Clear heat and detoxify, resolve phlegm and consolidate. Principal formula: modified Lianqiao Detoxification Decoction. Medicines: Scrophularia ningpoensis, Forsythia, Pueraria lobata, Talcum, Prunella vulgaris, Sagina japonica, Curcuma phaeocaulis, Scutellaria baicalensis, Paeonia lactiflora, Gardenia jasminoides, Sophora tonkinensis, Glycyrrhiza uralensis, etc.
2, Syndrome of Qi stagnation and Phlegm retention (including Qi-stagnation Phlegm retention):
Feeling of oppression in the chest, swelling in the hypochondria, feeling of fullness in the epigastrium and abdomen, multiple lumps in the neck, axilla, or inguinal region, without change in skin color, or with local swelling, or accompanied by low fever and night sweats, pale red tongue with thin white or thin yellow fur, wiry and slippery pulse, or thin and wiry.
Method of treatment: Soothe the liver, relieve depression, resolve phlegm and disperse knots. Main formula: Chaihu Shugan San combined with Xiaoluo Wan. Adjuvant drugs: Shengmuli, Xuan Shen, Xiakucao, Maozhua cao, Chaihu, Baishao, Zhiqua, Xiangfu, Yujin, Zhubei Mu, Zhigancao. For firm or large abdominal masses, add Sanlie, Yike; for multiple lymph nodes in the neck or other areas, add Luhufang, Tuber fuscum; for phlegm-heat, add Tianhuafen, Zhaoxiu; for low fever and night sweats, add Digenpi, Yin Chaihu; for concurrent spleen deficiency, add Dangshen, Fuling.
3. Syndrome of spleen deficiency and phlegm dampness:
General malaise, pale or slightly yellow complexion, pale lips, lymphadenopathy in the neck or inguinal region or peritoneal cavity, poor appetite, thin or loose stools, thin white or greasy tongue coating, pale tongue, thin pulse. This type is common after chemotherapy.
Method of treatment: Strengthen the spleen, replenish Qi, transform dampness and eliminate phlegm. Main formula: Liujunzi Decoction. Adjuvant drugs: Dangshen, Baizhu, Fuling, Chenpi, Banxia, Gancao, Maozhua cao, Luhufang. For white greasy tongue coating, add Huoxiang, Peilan, Cangzhu, Houpu. For enlarged and hard lymph nodes, add Sanlie, Yike, Luoshiteng, etc.
4. Syndrome of deficiency of both Qi and blood:
Common in advanced stages or after multiple courses of radiotherapy and chemotherapy, with lymph nodes or masses in the neck or inguinal region, or abdominal masses, pale or sallow complexion, dizziness and dizziness, palpitations, palpitations, shortness of breath, fatigue, loss of appetite, pale tongue, thin white fur, thin pulse, or weak and large pulse.
Principle of treatment: Invigorate the Qi, nourish the blood, soften hardness and disperse knots. Main formula: Bashen Decoction. Adjuvant drugs: Dangshen, Shudihuang, Jixueteng, Maozhua cao, Xiakucao, Baizhu, Fuling, Danggui, Baishao, Chuanxiong, Zhigancao. For obvious Qi deficiency, add Huangqi; for anorexia and loose stools, add Shentao, Biandou; for concurrent Yang deficiency, add Shuhuixi, Rougui. For large masses, add Sanlie, Yike.
5. Syndrome of Yin deficiency in liver and kidney (including Yin deficiency with fire):
Common in advanced stages or those with inherent Yin deficiency, or after multiple courses of radiotherapy, with lymph nodes or masses in the neck or inguinal region, or abdominal masses, afternoon feverishness, restlessness of the five interiors, insomnia and night sweats, dry mouth and sore throat, dizziness and dizziness, red tongue with little or no fur, wiry and thin pulse, or deep and thin pulse.
Principle of treatment: Tonify the liver and kidney, soften hardness and disperse accumulation. Main formula: Zhibai Dihuang Wan combined with Erzhi Wan. Adjuvant drugs: Shengdi, Shengmuli, Shanyao, Nuzhenzi, Hanliancao, Kunnan, Fuling, Zexie, Mudanpi, Zhimu, Huangbai. For severe fever and night sweats, add Baiwei, Digenpi; for dry mouth and constipation, add Yuju, Xuan Shen; for distension in the two sides of the chest, add Chuanlianzi, Yanhusuo; for anorexia and abdominal distension, add Shanzha, Jijin; for large masses, add Sanlie, Yike.
The treatment of external genital malignant lymphoma in Western medicine includes chemotherapy (radiotherapy): malignant lymphoma is sensitive to chemotherapy and radiotherapy. Macleod et al. proposed that for low-grade malignant focal external genital NHL, simple radiotherapy with a dose of 30 to 40 Gy (2 Gy per fraction) can be given. For moderately and highly malignant NHL, due to a high rate of systemic recurrence, chemotherapy or chemotherapy combined with radiotherapy is generally used. Bai Ping et al. suggested the sequential treatment of chemotherapy-radiotherapy-chemotherapy for malignant lymphoma of the external genitalia. The first 1 to 3 courses of chemotherapy are given to achieve complete remission of the tumor, followed by radiotherapy at the tumor site (18 to 30 Gy) to prevent local recurrence, and then consolidation chemotherapy for 2 to 3 courses.
II. Common chemotherapy regimens include
1. COP regimen:
Cyclophosphamide 800mg/, intravenous injection, on the first and 15th days; Vincristine 1.4mg/, intravenous injection, on the first day; Prednisone (prednisone) 100mg, oral, on the first to fifth day. Repeat one course every 3 weeks. The effective rate is over 80%.
2. CHOP regimen:
Cyclophosphamide 750mg/, intravenous infusion, on the first day; Doxorubicin (adriamycin) 50mg/, intravenous infusion, on the first day; Vincristine 1.4mg/, intravenous injection, on the first day; Prednisone (prednisone) 100mg, oral, on the first to fifth day. Repeat one course every 3 weeks. The effective rate is over 90%.
3. In addition, there are other regimens such as BACOP regimen (bleomycin, doxorubicin, cyclophosphamide, vincristine, and prednisone), MBACOD regimen (methotrexate, bleomycin, doxorubicin, cyclophosphamide, vincristine, and dexamethasone), and so on.
Bai Ping et al. used BACOP regimen chemotherapy for 4 courses and added local radiotherapy to treat vulvar malignant lymphoma. The tumor was completely relieved, but after 2 months, there was metastasis in the nasal cavity and left orbital, and PECB (cisplatin, etoposide, cyclophosphamide, and pingyangmycin) regimen was used for 5 courses after that, and complete remission was achieved. Follow-up for 4 years with no tumor recurrence. Complications include tumor ulceration and infection. Prognosis and prevention: Because most of the cases have a short follow-up period, it is impossible to evaluate the indicators for predicting the prognosis. Kaplan et al. reported that 8 of the 16 cases had local recurrence. Follow-up for 0 to 60 months (average 14 months), 8 cases survived, and the best case had 5 years of tumor-free survival. Vang et al. reported that 4 of the 10 primary vulvar NHL cases died within 1 year, and 1 case survived for 3 years without tumor recurrence; while 5 of the 8 secondary vulvar NHL cases died within 1 to 7 months after the diagnosis of vulvar NHL.