Ovarian leiomyosarcoma

　　The etiology of ovarian leiomyosarcoma is described as follows according to different types.

　　1. Leiomyoma

　　It may come from the vascular smooth muscle of the ovarian cortex or the interstitial stroma of the corpus luteum, or the vascular wall smooth muscle inside the ovarian ligament connected to the ovary. But the value of the above sources is not yet certain.

　　2. Smooth Muscle Sarcoma

　　It may come from smooth muscle.

　　3. Rhabdomyosarcoma

　　The source of tissue origin is still uncertain. It may come from the connective tissue of the ovary, it may be a unidirectional developing teratoma, it may be a malignant transformation of a mature cystic teratoma with excessive growth of malignant components accompanied by it, or it may be a unidirectional developing malignant mesenchymal mixed tumor.

　　Smooth muscle tumors often occur with uterine fibroids, and smooth muscle leiomyosarcomas are common with hemorrhage and necrosis. Rhabdomyosarcoma is often accompanied by hemorrhagic ascites, and metastasis is common. Therefore, high-risk groups need regular screening, and treatment should be timely once the disease occurs.

　　Ovarian leiomyosarcoma often has no symptoms when it is small. But according to the development of the disease course, the clinical manifestations of different types of leiomyomas are as follows.
　　1. Leiomyoma Clinical symptoms are often absent, mostly found by accident. When symptoms occur, they are often related to masses in the adnexa, manifested as abdominal enlargement and abdominal pain. Acute abdominal pain can be caused by torsion. Some scholars reported a case of a 68-year-old patient with ovarian leiomyoma who visited for recurrent slight vaginal bleeding for 1 year after menopause for 15 years. Pelvic examination often reveals ovarian solid masses. Ascites is rare, and there have been no reports of pleural effusion. It often occurs with uterine fibroids.
　　2. Smooth Muscle Sarcoma Symptoms and signs are related to abdominal and pelvic masses.
　　3. Rhabdomyosarcoma Symptoms often occur due to large tumors, usually growing rapidly. Abdominal masses can be found.

　　The etiology of ovarian leiomyosarcoma is not yet fully clear, therefore, there are currently no targeted preventive measures. High-risk groups should do regular physical examinations, early detection, and early treatment. Pay attention to follow-up monitoring of tumor markers after treatment to prevent recurrence.

　　Ovarian leiomyosarcoma can be diagnosed based on the patient's clinical manifestations, symptoms, and the following related examination results.
　　1. Laboratory examination:Tumor marker examination.
　　2. Other auxiliary examinations:Abdominal ultrasound, histopathological examination, laparoscopic examination.

　　Recommend 2 dietary therapy recipes suitable for patients with ovarian leiomyosarcoma.
　　1. Horse tail, bitter melon, Coix seed, pork soup
　　Horse tail herb 40g, bitter melon 500g, raw Coix seed 80g, pork 240g, honey dates 4 pieces, a little fine salt.
　　Preparation: Select fresh bitter melon, cut it open, remove the seeds, and cut it into pieces. Soak Verbena officinalis and Coix seed with clear water separately. Wash all the materials with clear water and set aside. Add an appropriate amount of clear water to the clay pot, boil with high heat first, then add all the above materials when the water boils again, change to medium heat and continue to boil for about 2 hours, add a little fine salt to season, and it can be drunk.
　　Effects: Clear heat and detoxify, diuretic and remove dampness, stop leukorrhea and pruritus.
　　Indications: Cancer of the reproductive system, with symptoms such as mixed leukorrhea, continuous dripping, fishy smell, lower abdominal pain, vulvar pruritus, insomnia and dreams, yellow and red urine, etc.
　　Note: People with weak spleen and stomach, pregnant women should not drink.
　　2. Solanum nigrum Luffa cylindrica Hedyotis diffusa pork soup
　　Smilax glabra 40g, Solanum nigrum 40g, Hedyotis diffusa 40g, Luffa cylindrica 40g, two honey dates, pork 240g, a little fine salt.
　　Preparation: Soak Solanum nigrum, Luffa cylindrica, Hedyotis diffusa and Smilax glabra separately with clear water. Wash all the materials with clear water and set aside. Put all the above materials into a clay pot, add an appropriate amount of clear water, boil with high heat first, then change to medium heat for about 2 hours, and season with a little fine salt.
　　Effects: Clear heat and detoxify, diuretic and remove dampness.
　　Indications: Cancer of the female reproductive system, with symptoms such as abundant leukorrhea, sticky texture, fishy smell, abundant menstrual blood, abdominal pain, short and red urine, frequent urination, urgency, etc.

　　The treatment of ovarian leiomyoma needs to be based on tumor classification and staging, and the treatment methods are as follows.
　　1. Leiomyoma The tumor is benign, and surgical resection can be curative. The scope of surgery can be selected according to age.
　　2. Smooth Muscle Sarcoma Primary ovarian smooth muscle sarcoma is mainly metastatic through blood vessels, although combined chemotherapy after surgery can improve the prognosis, the prognosis is usually poor.
　　3. Rhabdomyosarcoma Recommended combined chemotherapy includes dactinomycin (actinomycin D), vincristine, and cyclophosphamide. In addition, methotrexate is added, and leucovorin (folic acid) rescue and doxorubicin (adriamycin) are also effective.