Fibroma of the fingers and toes in infants

　　1. Etiology

　　The etiology of this disease is not yet clear and may be related to environmental factors, genetic factors, dietary factors, and emotional and nutritional factors during pregnancy.

　　2. Pathogenesis

　　The pathogenesis is not yet clear. Pathological examination shows many spindle-shaped fibroblasts and collagen fiber bundles arranged in a crisscross pattern in the dermis, which can extend to the subcutaneous tissue. Many fibroblasts have special eosinophilic inclusions near the nucleus, which are characteristic of diagnostic value.

　　The main complications and skin destruction of this disease are related, as the disease often accompanied by itching, children often scratch, and the integrity of the skin is destroyed. Therefore, skin bacterial infection or fungal infection may be induced by scratching, usually secondary to low body resistance, or long-term use of immunosuppressants, or patients with onychomycosis and other fungal infections. If there is concurrent bacterial infection, symptoms such as fever, skin swelling, ulceration, and purulent secretion may occur. Severe cases can lead to sepsis, so it should attract the attention of clinical doctors.

　　Common in infants under 1 year of age, 1/3 occur at birth, the lesions are usually solitary or several firm red smooth nodules, about 1cm in diameter, without subjective symptoms, prone to occur on the back and side of the distal fingers (toes), the thumb and big toe are not affected, and the damage does not spread.

　　The etiology of the disease is not yet clear, and it may be related to environmental factors, genetic factors, dietary factors, and emotional and nutritional factors during pregnancy. Therefore, it is not possible to prevent the disease by targeting the etiology. Early detection, early diagnosis, and early treatment are of great significance for indirect prevention of the disease. At the same time, it can also reduce the occurrence of infectious complications. For patients with infection, antibiotics should be applied locally and systemic treatment should be given as soon as possible.

　　Histopathology:There are many spindle-shaped fibroblasts and collagen fiber bundles arranged in a crisscross pattern in the dermis, which can extend to the subcutaneous tissue. Many fibroblasts have special eosinophilic inclusions near the nucleus, which are diagnostic features of value. Phosphotungstic acid hematoxylin staining shows deep red or Masson trichrome staining shows purple.

　　1. Foods that are good for infants and children with digital fibroma

　　Stay light in diet, eat more vegetables and fruits, and reasonably match the diet, paying attention to sufficient nutrition.

　　2. Foods that should not be eaten by infants and children with digital fibroma

　　Avoid smoking, drinking, spicy foods, greasy foods, and smoking. Avoid eating cold and raw foods.

　　(The above information is for reference only, please consult a doctor for details.)

　　1. Treatment

　　Since the etiology of the disease is not yet clear, it may be related to environmental factors, genetic factors, dietary factors, and emotional and nutritional factors during pregnancy. Therefore, it is not possible to carry out targeted treatment for the etiology. The main treatment is surgical resection, but it is very easy to recur. It is best to delay treatment and hope for spontaneous regression.

　　2. Prognosis

　　The thumb and big toe are not affected. The damage does not spread.