1. The实质of cavernous hemangioma is a malformation vascular cluster. The feeding artery and draining vein of the vascular cluster are normal caliber vessels. The blood flow in the tumor is slow, so angiography cannot be displayed. The blood stasis in the lesion of the malformation vascular cluster is also the cause of thrombosis and calcification in the malformation vessels. The appearance of the lesion is purple-red, with a surface that is like a mulberry ball and a section that is spongy or honeycomb-like. The vascular wall is composed of a single layer of endothelial cells, without a muscular layer and elastic layer. The lumen is filled with blood and may contain fresh or old thrombi; the tissue between the abnormal vessels is loose fibrous connective tissue, and there are no or very few brain parenchymal tissues between the vessels.
2. The texture of the tumor can be soft or hard, which is related to the blood content, calcification degree, and thrombus size in the malformation vascular cluster. The surrounding brain tissue has gliosis and yellow ferritin deposition. This ferritin is one of the causes of epilepsy in patients with cerebral cortical cavernous hemangioma.
3. Cavernous hemangiomas can occur at any part of the central nervous system, such as the cerebral cortex, basal ganglia, and brainstem (intracranial lesions), as well as the middle cranial fossa bottom, retina, and skull (extracranial lesions). About 19% of cases are multiple lesions. Patients with multiple cavernous hemangiomas often have vascular tumor lesions in other organs of the body. The size of the tumor varies, and the size and location of the tumor are directly related to the clinical manifestations. The size of the tumor ranges from 0.5 to 6 cm.
4. The lesions reported in China are often located in the middle cranial fossa extracranial dura, accounting for 70% to 80%, and a small number are located within the brain. Abroad, the most common lesions within the brain often have a tendency to spontaneously hemorrhage repeatedly in small amounts. Iron-containing pigment deposition and calcification points are often found in the tumor. Lesions outside the brain are often dominated by mass effect.