Syndrome of gastric rhythm disturbance

　　How is the syndrome of gastric rhythm disturbance caused? There are several reasons, which are briefly described as follows:

　　1. Nervous and humoral regulation disorders (30%)

　　The imbalance of excitatory and inhibitory neurotransmitters in the stomach. The change in the threshold of excitatory and inhibitory stimuli for gastric smooth muscle cells can be determined by various different enteric peptides in the central nervous system, which can determine the excitatory and inhibitory motor effects of the stomach. Other abnormal humoral factors include gastrin, motilin, serotonin, insulin, and so on.

　　2. Disease factors (25%)

　　Diseases that can often cause this syndrome include:

　　1. Gastric functional diseases. Such as functional dyspepsia, hyperactivity of the vagus nerve, etc.

　　2. Gastric organic diseases. Such as various gastritis, gastroesophageal reflux disease, peptic ulcer, gastric malignant tumors, post-gastrectomy, post-vagotomy, etc.

　　3. Systemic diseases. Such as intestinal motility disorders, portal hypertension syndrome with impaired liver function, cranial and brain diseases, etc.

　　3. Histopathological changes (28%)

　　Changes in histopathology can also cause this disease. Various diseases can cause inflammation of the submucosal plexus of the gastric mucosa and proliferation of connective tissue, as well as widespread damage to the autonomic nervous system by systemic diseases.

　　4. Drug effects (10%)

　　Drugs can also cause the onset of this disease, such as morphine, atropine, etc.

　　What diseases can be triggered by gastric rhythm disorder syndrome? Briefly described as follows:

　　1. Gastric functional diseases.Such as functional dyspepsia, hyperactivity of the vagus nerve, etc.

　　2. Gastric organic diseases.Such as various gastritis, gastroesophageal reflux disease, peptic ulcer, gastric malignant tumors, etc.

　　3. Systemic diseases.Such as intestinal motility disorders, portal hypertension syndrome with impaired liver function, cranial and brain diseases, etc.

　　What symptoms does gastric rhythm disorder syndrome have? Briefly described as follows:

　　Patients may have irregular step potential.(Pacesetter Potential, PP). There may be a rapid rhythm, reaching 9 times per minute (normal people have 3-4 times per minute), and even at the distal antrum, there may be ectopic rhythms, causing the retrograde propagation of PP to the proximal antrum, leading to severe vomiting or dry heaves. Women are more prone to this disease than men. Clinical manifestations include intermittent episodes of nausea, vomiting, epigastric pain, early satiety, and a few cases with bloating due to gastric retention. Gastric electromyography can record gastric electromyographic rhythm disorders, and the diagnosis needs to exclude organic diseases.

　　There are no special preventive measures for this disease. It is necessary to actively engage in physical exercise, strengthen immunity, and maintain a healthy lifestyle. This disease is often caused by a combination of factors, related to mental and psychological disorders, malocclusion, and poor oral hygiene habits. Therefore, the key to preventing this disease is to regulate the rhythm and order of life, eat a balanced diet, maintain oral hygiene, exercise regularly, and it is particularly important to treat abnormal occlusion relationships early.

　　What examinations should be done for gastric rhythm disorder syndrome? Briefly described as follows:

　　1. Gastric electrogastrogram examination.Gastric electric rhythm disorders can be recorded. Gastric emptying studies show varying degrees of gastric emptying dysfunction, mainly delayed emptying.

　　2. Endoscopic examination.The high-tech electronic colonoscopy instrument is inserted into the body through the natural cavity of the human body from the outside, and it can check diseases inside the body. It can directly observe the lesions inside the organ, determine their location and extent, and can also take photographs, perform biopsies, or scrape the surface, greatly improving the accuracy of cancer diagnosis and allowing for certain treatments.

　　3. X-ray examination.Gastrointestinal X-ray examination can show that the movement of the entire gastrointestinal tract accelerates, the colon pouch deepens, and the tension increases; sometimes due to colonic spasm, the descending colon and below appear as linear shadows, and the colonoscopy shows no obvious abnormalities in the colon mucosa.

　　4. Gastric juice analysis.The amount of gastric juice secretion is most affected by food, with the normal amount of gastric juice in an empty stomach being about 30-50ml. In the absence of food, the amount of gastric juice increases significantly, indicating excessive gastric secretion and reduced gastric motility. For example, during a gastric endoscopy, some patients have a large amount of fluid in the stomach, some appearing colorless and transparent foamy, some turbid and sticky, and some yellow-green.

　　What should be paid attention to in the diet and health care of patients with gastric dysrhythmia syndrome? Briefly described as follows:

　　1. Pay attention to regular meals.Many office workers do not like to eat breakfast and often forget to eat when they are busy. As a result, gastric acid and pepsin have nothing to digest, so they start to erode the gastric mucosa, which is easy to cause gastric ulcers and other gastrointestinal diseases.

　　2. Pay attention not to overeat at dinner.The scientific ratio of meals should be breakfast accounting for 30%, lunch 40%, and dinner 30%. Overeating at dinner or eating snacks before bed not only affects sleep but also causes the gastrointestinal tract to work excessively, which is easy to trigger diseases.

　　3. Pay attention to the cleanliness of the diet.During the spring and summer, Helicobacter pylori and various other bacteria reproduce rapidly. If the diet is not clean or fresh, it is easy to cause acute gastritis and other diseases.

　　What are the treatment methods for gastric dysrhythmia syndrome? Briefly described as follows:

　　Treatment can be chosen from chlorpromazine and anticholinergic drugs, but often with little effect. There are reports that domperidone (Motilium) can be taken 10-20mg each time, 3-4 times a day, which often has a certain effect; Cisapride can also be tried, 5-10mg each time, 2-3 times a day, taken before meals. For those who are ineffective, a partial gastrectomy and gastrojejunostomy can be performed.