Mycoplasma urinary tract infection

　　Urethritis is directly caused by Mycoplasma. The pathogenesis of the disease is unknown. Serum typing studies have shown that UU has at least 14 serotypes, with serotype 4 being the most common among UU isolated from NGU patients, and serotype 4 is also associated with asymptomatic pyuria. UU can cause some NGU (10% to 30%). However, UU is often detected in the urethra of individuals without urethritis, suggesting that only certain serotypes are pathogenic. Patients may be exposed to the pathogen for the first time, or there may be certain predisposing factors, such as mucosal immune deficiency. In addition, UU-induced urethritis can be subclinical and self-limiting. Another Mycoplasma isolated from the human reproductive tract is MG, and some chlamydial-negative, UU-negative patients may be caused by this Mycoplasma, especially in some chronic NGU cases. There is evidence that human Mycoplasma is closely related to ovarian abscess, salpingitis, abscess, hemorrhagic cystitis. UU can also cause prostatitis, epididymitis, infertility, urinary tract stones, pyelonephritis, and other conditions. Clinically, MH and UU can also cause infections outside the reproductive organs, and it has been found that MH sepsis can occur after renal transplantation, trauma, and urological and reproductive tract instrument operations.

　　The harm of Mycoplasma infection is significant, mainly manifested as male infertility. Mycoplasma infection destroys spermatogenic cells. There are a large number of spermatogenic cells in the seminiferous tubules of the testes, which develop and reproduce to form sperm. When Ureaplasma urealyticum infection enters the seminiferous tubules of the testes from the urethra, prostate, and other sites, it will destroy spermatogenic cells, leading to a decrease in sperm quality and quantity, and ultimately resulting in infertility.

　　The main manifestation of the harm caused by Mycoplasma infection in males is that they are prone to prostatitis and urethritis. After Mycoplasma infection through the urethra, patients may develop symptoms of urethritis and may subsequently develop chronic prostatitis. During the examination of prostatic fluid, active and swimming microbial colonies can be observed. Mycoplasma also continues to infect the seminal tract, seminal vesicles, and testes, affecting the quality of sperm and seminal fluid, leading to infertility. Observations have shown that Mycoplasma can cause infertility through the following stages.

　　Urethritis caused by Mycoplasma has clinical manifestations similar to those of general bacterial urinary tract infections. It may present with symptoms such as fever, lumbar pain, bladder irritation, and an increase in leukocytes in the urine sediment, which are indicative of acute pyelonephritis. It can also manifest as symptoms of lower urinary tract infection, with typical symptoms including urethral itching, varying degrees of dysuria and burning sensation, mild redness and swelling of the urethral orifice, and often with serous or seropurulent urethral discharge. The discharge is thinner and less frequent than that of gonococcal urethritis, or may only be observed as a white film on the urethral orifice upon waking.

　　Some patients may have no symptoms or signs of urinary discomfort, and the urine sediment may also show no increase in white blood cells, only positive culture of mycoplasma. Therefore, it is often easy to miss the diagnosis in clinical practice. The main site of infection in female patients is the cervix, with no obvious symptoms of urethritis, but may manifest as acute and chronic cervicitis, cervical erosion, increased leukorrhea, or mild difficulty in urination and frequent urination, and may also be asymptomatic.

　　Many friends are now suffering from the invasion of mycoplasma urinary tract infection, causing great impact and harm,困扰ing the health and life of patient friends. It is very important to actively understand and take effective preventive measures to avoid the occurrence of the disease, and it is also necessary for everyone to understand the preventive measures for mycoplasma urinary tract infection. The following are the preventive measures for mycoplasma urinary tract infection:

　　1. Urinate immediately after sexual activity:Go to the bathroom immediately after sexual intercourse, even if bacteria have entered the bladder, they can be excreted out of the body through urination.

　　2. Urinate in a timely manner:When urinating, urine washes away bacteria from the urethra and the vaginal opening, which has a natural cleaning effect.

　　3. Avoid contamination:The most common bacteria causing infection are Escherichia coli. Normally, it resides in the intestines and does not cause symptoms. However, if it enters the urethral opening from the anus, it can cause urethritis. Therefore, when wiping with clean toilet paper after defecation, you should wipe from front to back to avoid contamination of the vaginal opening. If there is a flushing device in the toilet, it is best to thoroughly flush the anal area.

　　4. Supplement vitamin C:Vitamin C can increase the acidity of urine, making it difficult for various bacteria that cause urinary tract infections to survive. Therefore, drinking rich vitamin beverages such as orange juice, lemon juice, and kiwi juice is beneficial for preventing urinary tract infections.

　　The occurrence of the disease requires timely treatment, and professional examination is also the key to clarifying the disease, which provides great help for the precise treatment of the disease. For mycoplasma urinary tract infection, it is also necessary to understand and professionally carry out the examination, so as to achieve the best treatment of the disease and ensure health.

　　The main examinations for mycoplasma urinary tract infection include

　　1. Mycoplasma isolation and culture:Collect fresh, clean middle urine and inoculate it into mycoplasma culture medium. Under suitable culture conditions, mycoplasma is easily isolated. When bacterial colonies are found, a homologous specific antibody inhibition test should be performed to classify the mycoplasma.

　　2. Serological diagnosis:The test is a practical method for diagnosing mycoplasma infection. Antigens made from mycoplasma can be used for complement fixation tests with patient serum, and the titer of serum complement fixation antibodies in the late stage of the disease is 4 times or more than the initial stage, which has diagnostic significance.

　　3. Other auxiliary examinations:Molecular biological diagnostic methods used in clinical trials include MG gap translation of whole genome DNA probes, UU-rRNA-specific DNA probes, and MH-rRNA gene probes, etc. Nucleic acid blotting tests using DNA probes for diagnosing genitourinary mycoplasma infections have slightly lower sensitivity (56%-63%), but higher specificity, which can differentiate various mycoplasmas or even inter-species biological types. To compensate for the lack of sensitivity, polymerase chain reaction is now widely used to assist in diagnosis.

　　The occurrence of mycoplasma urinary tract infection often brings a series of harms to patients, therefore, the treatment of the disease cannot be carried out blindly. Otherwise, it will only cause greater harm caused by the disease. Only by undergoing professional examination to clarify the disease can the best corresponding treatment be carried out.

　　Patients with mycoplasma urinary tract infection should consume adequate water, at least 3000cc per day, which can be replaced by other liquids, such as fruit juice, and should be consumed during the day to avoid frequent urination at night. Increasing the acidity of urine can prevent recurrence, such as eating meat, cheese, plums, grains, prunes, and raisins, and can also drink cranberry juice, red currant juice, and can also supplement vitamin C. Avoid spicy,刺激性, cold, and cool foods.

　　Traditional Chinese medicine is based on symptom differentiation and treatment. Generally, frequent urination, urgency, and pain are often due to downward damp-heat. The treatment of traditional Chinese medicine is to clear damp-heat, at the same time, regulate the body's viscera and Qi, strengthen the body to eliminate pathogens, rather than kill bacteria.

　　Although Western medicine works faster, long-term use is prone to develop drug resistance, damage human organs, and have惊人 toxic and side effects. Moreover, when bacteria enter the human body, they produce two substances, endotoxins and exotoxins. Exotoxins are produced by bacteria, while endotoxins are toxins produced after bacteria are killed and remain in the human body. Antibiotics can only kill bacteria but have no effect on endotoxins. Only by taking effective traditional Chinese medicine with antibiotics can the toxicity of antibiotics to the human body be effectively reduced, and better effects of clearing heat and detoxifying, and promoting diuresis can be achieved.