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Luteal insufficiency

  Luteal insufficiency, also known as luteal dysfunction, refers to the incomplete formation of the corpus luteum after ovulation in the ovary, leading to insufficient progesterone secretion. This results in the failure of the endometrium to transform in time, which is unfavorable for the implantation of the fertilized egg. Therefore, it often leads to infertility or habitual abortion. Luteal insufficiency refers to incomplete development of the corpus luteum, early atrophy, incomplete atrophy, insufficient progesterone secretion, and poor endometrial secretion, which cause menstrual disorders and syndromes of reproductive dysfunction.

  

Table of Contents

What are the causes of luteal insufficiency?
What complications can luteal insufficiency easily lead to?
What are the typical symptoms of luteal insufficiency?
4. How to prevent incomplete corpus luteum function
5. What kind of laboratory tests should be done for incomplete corpus luteum function
6. Diet taboos for patients with incomplete corpus luteum function
7. Conventional methods of Western medicine for the treatment of incomplete corpus luteum function

1. What are the causes of incomplete corpus luteum function

  The common causes of incomplete corpus luteum function mainly include the following aspects:

      1.Abnormal luteal phase, because the delayed secretion or changes of endometrial progesterone in women can cause incomplete corpus luteum function in women.

  2.Luteinizing hormone, follicle-stimulating hormone, because the secretion of follicle-stimulating hormone and luteinizing hormone in women is dysregulated, it can cause functional defects in the ovary and corpus luteum, resulting in abnormal secretion of progesterone during ovulation, leading to incomplete corpus luteum function.

  3.Endometriosis, endometriosis in women can cause a significant increase in prostaglandins released by the patient, thereby affecting the corpus luteum function in women.

  4.Systemic diseases, because malnutrition or physical weakness in patients can also lead to incomplete corpus luteum function in women.

2. What complications can incomplete corpus luteum function easily lead to

  One,Causes menstrual disorders in womenSome women with incomplete corpus luteum function may experience menstrual disorders, such as significantly shortened menstrual cycle, excessive menstruation, abnormal leukorrhea, frequent menstruation, and prolonged menstrual periods, causing great suffering to the female patients.

  Two,Induces habitual abortionThe incomplete corpus luteum function leads to insufficient secretion of progesterone, and the endometrium cannot be affected by progesterone to undergo the corresponding changes for conception. This leads to women finding it difficult to maintain pregnancy even after conception, resulting in phenomena such as abortion and habitual abortion.

  Three,Causes of infertilityDue to the inability of the corpus luteum to atrophy and regress in a cyclic manner or to only secrete a small amount of progesterone, the endometrium cannot be shed regularly at the normal time. The endometrium before menstruation still remains in the early secretory stage, and the endometrium is not sensitive to progesterone afterwards, with mild curvature of the glands. This results in women finding it difficult to conceive, eventually leading to infertility.

3. What are the typical symptoms of incomplete corpus luteum function

  Insufficient corpus luteum function can easily lead to poor follicle development, incomplete corpus luteum formation, and an imbalance in the ratio of estrogen and progesterone secreted by the corpus luteum itself. Infertility caused by incomplete corpus luteum function accounts for a significant number, about 3%-10% of all infertility. The main manifestations of incomplete corpus luteum function are shortening of the menstrual cycle, frequent menstruation, infertility, or abortion, and abortion mainly occurs in the early stage of pregnancy. Patients with this condition usually have no discomfort, but they may experience an absence of ovulation in several menstrual cycles, and sometimes they may have excessive and frequent menstruation or prolonged menstrual periods.

  1.DysmenorrheaWhen the corpus luteum function of women is abnormal and incomplete, women may experience symptoms such as shortening of the menstrual cycle and increased menstrual blood volume.

  2.AbortionIf the corpus luteum hormone is not secreted sufficiently in women, it can easily lead to a state where women are unable to become pregnant, and it is easy to cause abortion, and even habitual abortion may occur.

  3.Infertility:When corpus luteum function is abnormal, the female body will not be able to secrete appropriate progesterone to promote female pregnancy. Before the menstrual period, the internal hormone level of the female body will not rise due to this, making it difficult for women to become pregnant.

4,. How to prevent incomplete corpus luteum function

  1, After the menstrual period is clean, drink hawthorn, longan, and goji water every day.

  2, Pay attention to the hygiene of the reproductive organs and the vulva to avoid causing other diseases.

  3, Keep the spirit cheerful, negative emotions can lead to the suppression of pituitary function, causing infertility.

  4,节制性生活,过度频繁会使内分泌系统紊乱不利于受孕。5, eat more high-protein foods and ginger soup, lamb, vegetables, and fruits. Drink more water to keep the bowels通畅.

5. What laboratory tests need to be done for incomplete corpus luteum function

  One,Basal body temperature examination:Basal body temperature examination is one of the examination methods for incomplete corpus luteum function infertility, and it is also the simplest and most commonly used method. The slow rise of the high-temperature phase, the depression in the middle of the high-temperature phase, etc., all suggest luteal dysfunction, so the change of basal body temperature is also a symptom of incomplete corpus luteum function.

  Two,Blood progesterone level examination:What are the examination methods for incomplete corpus luteum function infertility? Checking the level of progesterone in the blood is also a method to check for incomplete corpus luteum function infertility. Experts say that the measurement of the level of progesterone in the blood is an important and reliable indicator for judging the corpus luteum function, and it is also the most common symptom of incomplete corpus luteum function.

  Three,Endometrial tissue imaging examination:Endometrial tissue imaging examination is also one of the examination methods for incomplete corpus luteum function infertility. Experts say that the time for taking endometrial tissue is mostly recommended to be in the middle of the luteal phase, that is, on the 7th day of the high-temperature phase.

  Four,Measure blood progesterone levels from the 18th to the 28th day of the menstrual cycle。If the content is lower than normal, it predicts incomplete corpus luteum function.

  Five,Ultrasonic detection of ovulation,the time from ovulation to the menstrual period should be about 14 days, if less than 12 days it is considered incomplete corpus luteum function.

  Six,Measuring the basal body temperature is the simplest methodHowever, it is also the most inaccurate method, measure the body temperature every morning, and then record it, and draw out the temperature chart.

  Seven,Dilatation and curettage, performed on the 26th day of the menstrual cycle,take endometrial tissue for histological examination, if the endometrial secretion is poor or two days behind the scraping day, then consider incomplete corpus luteum function.

6. Dietary taboos for patients with incomplete corpus luteum function

  Dietary health care for incomplete corpus luteum function

  Dietary regulation

  1, Lemon, which is rich in vitamin C, lemon oil, and bioflavonoids, etc., and the abundant vitamin C helps to promote blood circulation, aids in the absorption of iron, and can eliminate fatigue and refresh the spirit.

  2, Soybeans, which contain a variety of nutrients, can stabilize emotions, help with sleep, and alleviate abdominal pain. Soybeans also contain high levels of essential fatty acids, which have the beauty effect of improving rough skin, making them suitable for women during menstrual pain.

  3, Chicken, which is beneficial for replenishing qi and blood during the menstrual period, as chicken is rich in protein and other substances.

  4, Ginger, which can enhance appetite, promote metabolism, and keep the body warm, is an excellent warm food that is not suitable for eating alone.

7. The conventional method of Western medicine for treating luteal dysfunction

  (One)Progesterone Supplementation Therapy. According to statistics, when the progesterone supplementation therapy is applied properly, there is a 48% pregnancy rate. Generally, natural progesterone is preferred because natural progesterone has a good effect on promoting endometrial differentiation. It is not advisable to use synthetic progestins, because artificial synthetic progestins such as medroxyprogesterone acetate and norethindrone have the effect of dissolving the corpus luteum and the disadvantage of inhibiting the patient's own luteal hormone secretion. Generally, progesterone is injected intramuscularly 12.5 mg daily, starting 1-3 days after the ovulation or BBT rise, and continuing until the next menstrual period. This dose is sufficient to supplement general luteal deficiency. If pregnancy does not occur, the treatment is repeated in the next cycle. If pregnancy does not occur after three cycles of treatment, endometrial biopsy should be performed to observe whether an increase in the dose of progesterone is needed. It can also be injected intramuscularly with 250-500 mg of acid progesterone on the 17th or 18th day of the menstrual cycle to supplement the deficiency of progesterone.

  (Two)Luteal Stimulation Therapy. Chorionic gonadotropin (HCG) is an effective luteal function stimulator that can increase the synthesis of progesterone and prolong the lifespan of the corpus luteum. The medication should start 2-3 days after the expected ovulation, beginning with intramuscular injection of HCG 5,000 U every other day, for a total of 3-5 times, and 3 consecutive cycles as one course. Generally, the level of progesterone in the blood increases the day after injection. It is reported that about 80% of patients have an effect.

  (Three)Clomiphene Treatment. The theoretical basis is that the above two drugs promote the secretion of LH-RH by the hypothalamus, thereby causing the pituitary to secrete

  FSH and LH increase, leading to the development and maturation of the ovary before ovulation, causing the luteal cells to secrete more progesterone after ovulation. Therefore, it is effective for luteal dysfunction caused by insufficient FSH and LH secretion, but the efficacy is not stable. The medication method is to take clomiphene 50-100mg daily starting from the 5th day of the menstrual cycle, for 5 consecutive days.

  (Four)Bromocriptine TreatmentFor luteal dysfunction caused by hyperprolactinemia, bromocriptine (CB1-54) treatment has certain efficacy.

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