Chlamydia Trachomatis infection in the reproductive tract during pregnancy

　　There are two forms of chlamydial infection in pregnant women: recent active infection and latent chlamydial infection that is activated due to pregnancy. The risk factors for chlamydial cervicitis in pregnant women include: a young age of onset of sexual activity, multiple sexual partners, low educational level, not using barrier contraception, suffering from trachoma and severe cervical erosion, etc. If any of the above risks are found in pregnant women, it is necessary to test for cervical chlamydia in a timely manner. Pregnant women with active chlamydial infection are at risk of premature rupture of membranes. If it occurs in the early stages of pregnancy, it is easy to cause abortion. It is important to actively avoid infection.

　　1. Chlamydial infection in the reproductive tract during pregnancy

　　Chlamydial infection can cause spontaneous abortion, stillbirth, premature rupture of membranes, preterm birth, increased low birth weight infants, neonatal conjunctivitis, and neonatal pneumonia.

　　2. Reproductive tract of pregnant women

　　Chlamydial infection can occur through vertical transmission, including intrauterine infection, birth canal infection, and postpartum infection. Newborns mainly become infected through the birth canal. Neonatal chlamydial infection is a systemic disease, and chlamydial infection in newborns most commonly invades the conjunctiva to form conjunctivitis, manifested as purulent and mucopurulent discharge, conjunctival congestion, papillary hyperplasia, and the course can last for 1-3 months. Neonatal chlamydial pneumonia can also occur.

　　Clinical characteristics include asymptomatic or mild symptoms, making it difficult for patients to detect them, and the course of the disease is protracted. The manifestations of infection in pregnant women include the following:

　　1. Cervical mucositis

　　The cervical canal is the most common site of chlamydial infection, with 70% to 90% of chlamydial cervical mucositis being asymptomatic. Symptoms include increased vaginal discharge, which is purulent and mucus-like, post-coital bleeding or intermenstrual bleeding. Examination shows purulent cervical canal secretion, red and swollen cervix, mucosal inversion, and increased fragility.

　　2. Urethritis

　　Such as urgency of urination, frequent urination, dysuria, etc.

　　3. Endometritis

　　30% to 40% of cervicitis can ascend to endometritis, manifested as lower abdominal pain, increased vaginal discharge, and irregular slight vaginal bleeding.

　　4. Effects on the fetus and newborn

　　Active infection can cause abortion, preterm birth, premature rupture of membranes, low birth weight, etc. In newborns delivered by untreated chlamydial infection pregnant women, 20% to 50% may develop neonatal conjunctivitis, and 10% to 20% may develop chlamydial pneumonia.

　　There are two forms of chlamydial infection in pregnant women: recent active infection and latent chlamydial infection that is activated due to pregnancy. The risk factors for chlamydial cervicitis in pregnant women include: a young age of onset of sexual activity, multiple sexual partners, low educational level, not using barrier contraception, suffering from trachoma and severe cervical erosion, etc. If any of the above risks are found in pregnant women, it is necessary to test for cervical chlamydia in a timely manner. Pregnant women with active chlamydial infection are at risk of premature rupture of membranes. If it occurs in the early stages of pregnancy, it is easy to cause abortion. It is important to actively avoid infection.

　　1. Cytological examination

　　Inclusions are found within the epithelial cells under the microscope.

　　2. Chlamydia trachomatis culture

　　It is the most sensitive and specific method for diagnosing Chlamydia trachomatis infection.

　　3. Chlamydia trachomatis antigen detection

　　Including direct immunofluorescence and enzyme-linked immunosorbent assay.

　　4. Chlamydia trachomatis nucleic acid detection

　　PCR technology has high sensitivity, and Chlamydia DNA can be detected even when cell culture is negative, but it should be prevented from false positives caused by contamination.

　　5. Serum antibody detection

　　Chlamydia IgG, IgM.

　　What foods should pregnant women with reproductive tract Chlamydia trachomatis infection eat for good health

　　Eat light, eat more vegetables and fruits, and reasonably match the diet, pay attention to adequate nutrition.

　　What foods should pregnant women with reproductive tract Chlamydia trachomatis infection avoid

　　Avoid smoking, drinking, spicy and pungent foods. Avoid greasy, smoking, drinking, and spicy foods. Avoid cold and raw foods.

　　If Chlamydia is detected in the cervix of a pregnant woman, medication should be taken promptly. Erythromycin 0.5g, taken orally every 6 hours, for 7 consecutive days, or 0.25g, taken orally every 6 hours for 14 consecutive days, has a significant effect on the negative conversion of cervical Chlamydia and is also an effective means of preventing neonatal Chlamydia infection. For newborns at risk of Chlamydia infection, they should be hospitalized for at least one week to prove the presence or absence of Chlamydia infection. If diagnosed with Chlamydial conjunctivitis, 1% silver nitrate solution can be used for eye drops, although the effect is good, it cannot prevent the occurrence of Chlamydial pneumonia. Oral erythromycin: 50mg/kg, taken orally in 4 divided doses, for 14 consecutive days, can prevent the occurrence of Chlamydial pneumonia.