Vulvar adenocarcinoma

　　The etiology of vulvar adenocarcinoma is currently unknown and may be related to various factors. Ten percent of patients with vulvar adenocarcinoma have a history of vulvar adenitis, and some believe it may be related to vulvar and vulvar gland infections.

　　After the rupture of Bartholin's gland adenocarcinoma, the cancer tissue is exposed, and combined with low body immunity and defense ability, it can be complicated with infection. Incomplete resection of Bartholin's gland adenocarcinoma often leads to local recurrence, so it needs to be paid attention to by doctors and patients.

　　Due to the deep location of Bartholin's gland adenocarcinoma, there are no symptoms in the early stage, and it is often misdiagnosed as Bartholin's gland inflammation. Women after menopause with Bartholin's gland swelling must first exclude malignant tumors. The most common symptoms of Bartholin's gland adenocarcinoma are vaginal pain and swelling, with hard nodules. In the middle and late stages, the Bartholin's gland mass ulcerates, ulcers appear, and complications such as abscesses, effusions, or bleeding can occur due to infection. The tumor mass infiltrates the surrounding area, involving the vaginal rectal septum or perineum, and can cause pain and swelling in the vagina or perineum.

　　During physical examination, swelling can be seen below the lower third of the labia, a hard, nodular mass can be felt, and the skin on the mass surface is intact. With the development of the tumor, the mass ulcerates and becomes infected, infiltrating the vagina or perineum. The inguinal lymph nodes swell due to the metastasis of cancer. It is extremely rare to have bilateral primary Bartholin's gland adenocarcinoma at the same time.

　　Bartholin's gland adenocarcinoma currently has no effective preventive measures due to the unknown cause. In terms of prevention, regular physical examinations, early diagnosis, early treatment, and good follow-up are crucial for the prognosis of patients.

　　In addition to clinical manifestations, blood routine examination, secretion examination, tumor marker examination, tissue pathology examination, pelvic lymph node CT scan, lymphography examination, and other examinations are required for the diagnosis of Bartholin's gland adenocarcinoma.

　　Patients' diet should be light, eat more fresh fruits and vegetables, drink more water, eat more nutritious and easily digestible foods, and supplement more protein. Spicy,刺激性, and greasy foods will worsen the condition, and patients should avoid eating them.

　　This disease should be treated with radical vulvectomy and inguinal lymph node dissection. The Bartholin's gland adenocarcinoma can spread to deep pelvic lymph nodes without passing through the inguinal lymph nodes, and it can be considered to perform routine ipsilateral inguinal and pelvic lymph node dissection. The adenoid cystadenocarcinoma of the Bartholin's gland has a slightly lower degree of malignancy, and early patients can consider only undergoing a wide excision of the vulva.